摘要
以传明酸、烟酰胺、4-甲氧基水杨酸钾和光果甘草根提取物为主要美白活性成分制备了一种美白霜。该美白霜分布均匀、无颗粒感、细腻柔滑、稠度适宜,稳定性良好;采用3D黑素皮肤模型体外测试和人体试验的方法对其进行了美白功效评价。3D黑素皮肤模型体外测试结果表明,该美白霜对黑色素的合成或转运有显著的抑制作用,具有优异的体外美白功效;人体试验结果表明,使用该美白霜4周后,受试者皮肤黑色素含量(MI值)明显降低,肌肤白度(L*值)和明亮度(ITA°值)增加,说明其具有良好的美白效果。
Tranexamic acid, nicotinamide, potassium 4 - methoxysalicylate and Glycyrrhiza glabra （ licorice ） root extract were used as the main whitening active ingredients to prepare a human - skin whitening cream. The prepared human -skin whitening cream is uniform, no granulous feeling, delicate and smooth, with good consistency and stability. The whitening effect was evaluated by 3D melanin skin model in vitro test and volunteer＇s human - skin test. The results of 3D melanin skin model in vitro test show that the prepared human - skin whitening cream displays significant inhibitory effect on the synthesis or transfer of melanin, which indicates that it has excellent whitening effect in vitro. Human - skin test results show that the skin melanin content （MI value） of the volunteer＇s skin is significantly reduced, and their skin whiteness （L^＊ value） and brightness （ITA° value） are increased after using the prepared human - skin whitening cream for 4 weeks, indicating that the prepared human -skin whitening cream displays a good effect.
出处
《日用化学工业》
CAS
CSCD
北大核心
2017年第9期512-516,521,共6页
China Surfactant Detergent & Cosmetics
