摘要
目的:探讨补肾断续汤联合髓内钉固定治疗胫骨中下段骨折不愈合的临床疗效。方法:将50例胫骨中下段骨折不愈合患者随机分为两组。对照组行髓内钉固定术;治疗组在髓内钉固定术后予补肾断续汤治疗。比较两组临床疗效,结骨痂时间及骨折愈合时间,术后8个月膝、踝关节功能优良率,比较两组术后红细胞刚性指数(IR)、红细胞聚集指数(AI)、高切全血黏度(WBV)、低切WBV及血浆黏度(PV)等血液流变学指标。结果:术后3个月,治疗组总有效率为96.0%,对照组总有效率为76.0%,治疗组优于对照组(P<0.05);治疗组住院时间、结骨痂时间及骨折愈合时间均短于对照组(P<0.01);术后8个月,治疗组膝、踝关节功能优良率为88.0%,对照组膝、踝关节功能优良率为64.0%,治疗组优于对照组(P<0.05);术后1、2、3个月两组比较,治疗组血液流变学指标均优于对照组(P<0.01)。结论:补肾断续汤联合髓内钉固定治疗胫骨中下段骨折不愈合能迅速缓解骨痛症状,改善机体微循环,缩短骨折愈合时间,提升关节功能。
Objectives： To investigate the effect of Bushen Duanxu Decoction with intramedullary nail on nonunion of tibial middle and lower fractures and hemorheology. Methods： The 50 cases with nonunion of tibial middle and lower fractures were divide them into two groups randomly, install intramedullary nail for cases in control group, install intramedullary nail and Bushen Duanxu Decoction for cases in research group. The curative effect, hospitalization time, bone callus time, fracture healing time, the excellent and good rate of knee and ankle joint function in 8th postoperative month, red cell index of rigidity （IR）, red cell assembling index （AI）, high shear whole blood viscosity （WBV）, low shear WBV and plasma viscosity （PV） at any postoperative time were recorded and compared between the two groups. Results： The overall effective rate was 96.0% in treatment group and 76.0% in control group, and the treatment group showed better effect than than the control group at 3rd postoperative month （P〈0.05）. The treatment group showed shorter hospitalization time and bone callus time and fracture healing time than the control group （P〈0.01）. At 8th postoperative month, the excellent and good rate of knee and ankle joint function was 88.0% in treatment group and 64.0% in control group, and the treatment group showed higher excellent and good rate than the control group （P〈0.05）. The treatment group showed better hemorrheological indexes than the control group at 1st, 24 and 3rd postoperative month （P〈0.01）. Conclusion： The application of Bushen Duanxu Decoction with intramedullary nail helps patient with tibial middle and lower fractures to release bone pain symptoms, improve microcirculation, shorten fracture healing time, and improve joint function.
作者
宋军峰
肖存
张宝田
张照亮
SONG Jun-feng XIAO Cun ZHANG Bao-tian ZHANG Zhao-liang(Gaoyi County Hospital, Shijiazhuan Hebei 051330, China Yixian County Hospital, Baoding Hebei 074200, China)
出处
《中医药导报》
2017年第17期81-84,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
河北省中医药管理局科研计划课题(2016303)
关键词
胫骨中下段骨折不愈合
补肾断续汤
髓内钉固定术
血液流变学
nonunion of tibial middle and lower fractures
Bushen Duanxu Decoction
intramedullary nail fixing surgery
hemorheology
