摘要
肝衰竭、急性失代偿期肝硬化等重症肝病病情危重,病死率高,其预后与早期预警、及时动态评估、综合有效的治疗密切相关。患者需要祛除致病因素、器官支持、并发症防治等一系列有效的临床管理措施。内科治疗-人工肝-肝移植是目前重症肝病的重要治疗模式。粒细胞集落刺激因子、干细胞治疗、生物型人工肝等新的探索曙光在前,非选择性β受体阻滞剂仍存在一定争议。
Severe liver diseases such as liver failure and acute decompensated cirrhosis have critical conditions and high mortality rates,and the prognosis of such patients is closely associated with early warning,timely dynamic assessment,and comprehensive and effective therapy.The patients require a series of effective clinical management measures for elimination of causative factors,organ support,and prevention and treatment of complications. Medical treatment-artificial liver-liver transplantation is an important modality for severe liver diseases. Granulocyte colony-stimulating factor,stem cell therapy,and bioartificial liver have a promising future,while there are still controversies over non-selective β-blocker. This article reviews the hotspots in the clinical management of severe liver diseases.
作者
吕佳昱
韩涛
LYU Jiayu HAN Tao.(Department of Hepatology and Gastroenterology, Tianjin Third Central Hospital, Tianjin Medical University, Tianfin Key Laboratory of Artificial Cell, Tianjin Institute of Hepatobiliary Disease, Tianjin 300170, China)
出处
《临床肝胆病杂志》
CAS
2017年第9期1617-1620,共4页
Journal of Clinical Hepatology
关键词
肝功能衰竭
肝硬化
肝
人工
肝移植
诊断
治疗
述评
liver failure
liver cirrhosis
liver
artificial
liver transplantation
diagnosis
treatment
editorial
