摘要
目的分析右美托咪定对扁桃体摘除术麻醉的影响情况。方法选取2014年1月—2017年4月我院收治的行扁桃体摘除术患者66例作为研究对象。依照就诊顺序,将患者随机平均分为观察组以及对照组,每组各33例。所有患者均采用全凭静脉麻醉,观察组麻醉维持期持续泵注,持续静脉泵入剂量为0.5μg/(kg·h)的右美托咪定;对照组泵注相同体积的0.9%NS溶液,分析两组患者的麻醉相关结果。结果观察组患者的VAS以及PAED分数与对照组对比,差异均具有统计学意义(P<0.05)。观察组患者阿托品使用次数多于对照组,差异具有统计学意义(P<0.05)。观察组患者的苏醒时间以及PACU停留时间均短于对照组,麻醉起效时间长于对照组,组间数据对比,差异均具有统计学意义(P<0.05)。观察组患者术后血清内疼痛介质含量低于对照组,差异均具有统计学意义(P<0.05)。结论右美托咪定能够有效预防麻醉苏醒期躁动发生,安全性强,可减缓扁桃体摘除者术后并发症发生率,提升麻醉苏醒期舒适度。
Objective To analyze the effect of dexmedetomidinc on anesthesia during tonsillectomy. Methods 66 cases of tonsillectomy in our hospital from January 2014 to April 2017 were selected as the study subjects. The patients were randomly divided into the observation group and the control group according to the order of visits, with 33 patients in each group. All patients were treated with total intravenous anesthesia, the patients in the observation group received continuous pump infusion during the anesthesia maintenance period and the continuous intravenous infusion of dexmedetomidine at a dose of 0.5 μg/（kg·h）. Patients in the control group were injected with the same volume of 0.9% NS solution, and the anesthetic related results of the two groups were analyzed. Results The VAS and PAED scores in the observation group were compared with those in the control group, the differences were statistically significant （P 〈 0.05）. The use of atropine in the observation group was more than that in the cotatrol group, the difference was statistically significant （P 〈 0.05）. The recovery time and PACU residence time of the observation group were shorter than those of the control group, the onset time of anesthesia was longer than that of the control group, and the data between groups were compared, The differences were statistically significant （P 〈 0.05）. The level of serum pain mediators in the observation group was lower than that in the control group, The differences were statistically significant （P 〈 0.05）. Conclusion Dexmedetomidine can effectively prevent the emergence of anesthesia, restlessness, restlessness, safety, slow down the incidence of postoperative complications of tonsiUeetomy, and improve the comfort of anesthesia recovery period.
作者
李东
LI Dong(Anesthesiology Department, Zhangjiagang Traditional Chinese Medicine Hospital, Zhangjiagang Jiangsu 215600, China)
出处
《中国继续医学教育》
2017年第21期71-72,共2页
China Continuing Medical Education
关键词
右美托咪定
扁桃体摘除术
麻醉
苏醒期
躁动
控制效果
dexmedetomidine
tonsillectomy
anesthesia
recovery period
restlessness
control effect
