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阿奇霉素联合小儿消积止咳口服液治疗小儿支原体肺炎的临床疗效分析 被引量:8

Analysis of Clinical Curative Effect of Azithromycin and Xiaoji Zhike Oral Solution in Treatment of Mycoplasma Pneumonia in Children
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摘要 目的研究联合阿奇霉素以及小儿消积止咳口服液治疗小儿支原体肺炎的疗效,并观察两组患儿的不良反应发生情况。方法对该院2014年5月—2016年5月期间所收治的47例小儿支原体肺炎患儿进行回顾性分析,按治疗方法的不同将其分为研究组(n=25)和对照组(n=22),两组患儿在入院后均行常规退热、止咳、化痰治疗,随后对照组患儿应用阿奇霉素治疗,研究组患儿在此基础上行小儿消积止咳口服液,对比分析两组患儿临床体征消失时间以及的临床效果,对患儿治疗良反应发生情况进行详细记录。结果研究组患儿的治疗总有效率对比对照组差异有统计学意义,退热时间、肺部啰音消失时间、咳嗽消失时间与X线片肺部病灶消失时间(2.41±1.18)h,(6.08±2.19)d,(5.63±2.11)d,(10.48±2.57)d明显短于对照组(4.49±1.87)h,(9.94±2.85)d,(8.87±2.06)d,(12.94±2.69)d,两组差异有统计学意义(P<0.05)。两组患儿不良反应发生情况方面比较,差异无统计学意义(P>0.05)。结论阿奇霉素与小儿消积止咳口服液联合治疗小儿支原体肺炎的效果明显,能够有效改善患儿的炎症细胞水平,值得应用。 Objective To re se a rch th e cu ra tive effect of azithromycin an d xiaoji zhike oral solution in tre a tm en t of my-coplasma pneumonia in chi ldren and observe the occur rence of adverse reactions of the two groups. Methods 4 7 cases of chi ldren with mycoplasma pneumonia admit ted and treated in our hospi tal from May 2014 to May 2016 were selected and divided into two groups according to the admis sion time, both groups adopted the routine treatment, and then the control group were treated with azithromycin, while the research group, while the research group adopted the Xiaoji Zhike Oral Solution on the bas is of the control group, and the cl inical vital sign disappearance time and cl inical effect were compared between the two groups, and the occur rence of adverse reactions were recorded in detail . Results The difference in the total effective rate between the two groups was obvious, and the defervescence time, lung rale disap-pearance time, cough disappearance time and X ray lung lesions disappearance time were obviously shorter than those in the control group, [ (2.41±1.18)h,(6.08±2.19)d,(5.63±2.11)d,(10.48±2.57)d vs (4.49±1.87)h,(9.94±2.85)d,(8.87±2.06)d,(12.94±2.69)d] , (P〈0.05), and the differences were s tat is t ically signif icant, and the difference in the occur rence of ad-verse reactions between the two groups was not s tat is t ically signif icant(P〉0.05) . Conclusion The effect of azithromycin and xiaoji zhike oral solution in treatment of mycoplasma pneumonia in chi ldren is obvious, which can effectively im-prove the inflammatory cel l level of chi ldren, and it is worth applicat ion.
作者 张敏
出处 《系统医学》 2017年第9期73-75,共3页 Systems Medicine
关键词 阿奇霉素 小儿消积止咳口服液 小儿支原体肺炎 Azithromycin Xiaoji zhike o ral solution in ch i ld ren Mycoplasma p neumo n ia in ch i ld ren
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