摘要
目的:观察益髓补肾方对恶性血液病患者围化疗期生活质量的影响。方法:选取100例恶性血液病患者作为研究对象,按照随机数字法分为益髓补肾方组及对照组,各50例,益髓补肾方组在围化疗期给予益髓补肾方+化疗治疗,对照组在围化疗期给予单纯化疗,在一疗程的化疗结束后以问卷形式行生活质量的评估,共计4个疗程。结果:益髓补肾方组患者总有效率均优于对照组(44.00%/30.00%),不良反应的发生率低于对照组(30.00%/60.00%),差异均有统计学意义(P<0.05);治疗后,益髓补肾方组患者总体健康状况、功能量表各项评分均高于对照组(P<0.05);症状量表各项目评分均低于对照组(P<0.05);六个单项测量项目除经济困难外,益髓补肾方组各指标评分均低于对照组(P<0.05)。结论:益髓补肾方联合化疗治疗HM患者效果显著,可有效提高其治疗后的生活质量,值得借鉴和推广。
Objective ： To investigate the effects of Yisu Bushen Recipe on quality of life of patients with malignant hematologic diseases during chemotherapy. Methods ： A total of 100 patients with hematological malignancies were randomly divided into two groups： Yishen Bushen Recipe group and control group, 50 cases in each group. Yisui Bushen Recipe group were treated with Yishen Bushen Recipe ＋ chemotherapy. The control group were treated with the chemotherapy alone. The quality of life was assessed by questionnaires at the end of one course of chemotherapy, a total of 4 courses. Results ： The total effective rate of the patients of Yishen Bushen Recipe group was better than that of the control group （44.00%/30.00%）. The incidence of toxicity was lower than that of the control group （30.00%/60.00%） . The difference was statistically significant （ P 〈 0. 05 ）. After treatment, the scores of the general health status and the functional scale of the patients in Yisui Bushen Decoction group were higher than those in the control group （P 〈 0. 05）. The symptom scores of the symptom scale were lower than those of the control group （P 〈 0. 05 ）. In addition to economic difficulties, the scores of all the six items were lower than those of the control group （P 〈 0. 05）. Conclusion ： Yiwei Bushen Recipe combined with chemotherapy is safe and reliable for the treatment of malignant hematologic disease, which can significantly improve the quality of life of patients. It is worthy of wider promotion and application.
出处
《中华中医药学刊》
CAS
北大核心
2017年第10期2657-2660,共4页
Chinese Archives of Traditional Chinese Medicine
基金
河北省中医药管理局项目(2017033)
关键词
益髓补肾方
恶性血液病
化疗
生活质量
Yisui Bushen Recipe
malignant hematopathy
chemotherapy
quality of life
