期刊文献+

不同手术方式治疗宫颈高级别上皮内瘤变LEEP术后切缘阳性病例分析 被引量:8

下载PDF
导出
摘要 目的:探讨不同术式治疗宫颈高级别上皮内瘤变(CINⅢ)LEEP术后切缘阳性临床意义。方法:收集298例因CINⅢLEEP术后病理切缘阳性住院再次手术患者,根据切缘累及情况,结合患者意愿、年龄及生育要求等自身情况,分为2组,A组行宫颈冷刀锥切术123例,B组行全子宫切除术175例,对比2组术后标本病理病变残留及术后随访复发情况,分析不同术式治疗CINⅢLEEP术后切缘阳性的意义。结果:A组123例行全麻或腰麻下冷刀锥切术,术后病理示56.10%(69/123)有宫颈残余病变,B组175例行全子宫切除术,术后病理示有宫颈残余病变为54.86%(96/175)。A、B组术后病理病变残余率经χ~2检验后差异无统计学意义(χ~2=0.045,P=0.832);A组术后复发率为7.87%。B组术后复发率为1.79%。A、B组之间经χ~2检验,差异无统计学意义(χ~2=3.895,P=0.048)。结论:CINⅢLEEP术后切缘阳性患者均可行再次手术,再次手术方式既可选择冷刀锥切术,亦可选用全子宫切除术,2种手术方式均可达到理想的治疗效果,具体手术方式需结合患者年龄及生育等要求,但对于所有切缘阳性患者行再次手术亦存在过度治疗的风险。
出处 《长治医学院学报》 2017年第4期287-290,共4页 Journal of Changzhi Medical College
  • 相关文献

参考文献5

二级参考文献66

  • 1戴志琴,潘凌亚,黄惠芳,郎景和.宫颈上皮内瘤变手术后边缘的评价[J].中华肿瘤杂志,2007,29(2):153-154. 被引量:10
  • 2Kyrgiou M, Tsoumpou I, Vrekoussis T, et al. The up-to-date evidence on colposcopy practice and treatment of cervical intraepithelial neoplasia: the Cochrane calposcopy & cervical cytopathology collaborative group ( C5 group ) approach. Cancer Treat Rev .2006.32,516-523.
  • 3Wright TC Jr, Massad LS, Dunton C J, et al. 2006 consensus uidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ. Am J Obstet Gynecol, 2007, 197:340-345.
  • 4Benedet JL, Bender H, Jones H 3rd, et al. FIGO staging classifications and clinical practice guidelines in the management of gynecologic carcinomas. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet,2000,70:209-262.
  • 5Ghaem-Maghami S, Sagi S, Majeed G, et al. Incomplete excision of cervical intraepithelial neoplasia and risk of treatment failure : a meta-analysis. Lancet Oncol, 2007, 8 : 985-993.
  • 6薛风霞.宫颈炎症//乐杰.妇产科学.6版.北京:人民卫生出版社,2004:264-267.
  • 7Kyrgiou M, Koliopoulos G, Martin-Hirsch P, et al. Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis. Lancet ,2006,367:489-498.
  • 8Bruinsma F, Lumley J, Tan J, et al. Precancerous changes in the cervix and risk of subsequent preterm biah. BJOG ,2007 ,114 :70-80.
  • 9Soutter WP, Sasieni P, Panoskaltsis T. Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia. Int J Cancer,2006,118:2048-2055.
  • 10Kalliala I, Anttila A, Pukkala E, et al. Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia: retrospective cohort study. BMJ,2005,331 : 1183-1185.

共引文献54

同被引文献55

引证文献8

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部