摘要
目的探讨老年人骨质疏松症与多种慢性疾病的相关性。方法选取2013年4月~2016年9月于解放军第一八一医院老年科住院患者373例,其中,60岁以上老年患者323例,在入院24 h内调查患者年龄、性别、身高、体重指数(BMI),根据既往病史及入院后检查了解其是否合并2型糖尿病、高血压、冠心病、慢性阻塞性肺疾病(COPD)、脑卒中、慢性肾脏疾病、白内障、脊椎退变、泌尿系结石、胆道结石等常见慢性疾病,同时测量L_2~L_4以及双侧股骨颈、粗隆及Ward's三角区骨密度(BMD),取T-score低值,分别对全部患者及60岁以上老年患者进行偏相关分析。结果偏相关分析结果显示,全部患者中BMD与性别、年龄、BMI、2型糖尿病、脑卒中、白内障、胸椎退行性病变、膝关节退行性病变、胆道结石相关(P<0.05),60岁以上老年患者BMD与性别、BMI、2型糖尿病、高血压、冠心病、脑卒中、膝关节退行性病变、胆道结石有关(P<0.05)。结论 BMD与性别、BMI、2型糖尿病、脑卒中、膝关节退行性病变及胆道结石等因素相关,而老年患者BMD同时与高血压等相关,提示治疗和预防上述慢性疾病可能有助于骨质疏松的防治。
Objective To discuss the correlation between osteoporosis and various chronic diseases in the elderly. Methods 373 patients in Geriatrics Department of 181th Hospital of PLA from April 2013 to September 2016 were selected as the whole patients, in which the elderly patients over 60 years old were selected as the elderly. Within 24 hours of admission, age, sex , height and BMI, at the same time, according their anamnesis and hospital examination, whether suffered from common chronic diseases such as type-2 diabetes, hypertension, coronary heart disease, COPD, cerebral apoplexy, malnutrition, chronic kidney disease, cataract, spinal degeneration, urinary tract stones and biliary calculi of these patients were investigated. The BMD of L2-L4, bilateral collum femoris, oblique eminence of cuboid bone and Ward＇s triangle were measured, the low values of T-scores were taken. Then the relation between the foregoing investigation＇s data and BMD in all patients and the elderly were analyzed by partial correlation analysis. Results Partial correlation analysis showed that in all patients BMD was related with sex, age, BMI, type-2 diabetes, stroke, cataracts, thoracic vertebra degeneration, knee-joint degeneration, biliary calculi （P 〈 0.05）. But in the elderly, the BMD was related with sex, BMI, type-2 diabetes, hypertension, coronary heart disease, cerebral apoplexy, knee-joint degeneration, biliary calculi （P 〈 0.05）. Conclusion BMD is related with multiple factors and various chronic diseases such as gender, BMI, type-2 diabetes, stroke , knee-joint degeneration, biliary calculi and so on, meanwhile, BMD in the elderly is related to hypertension and others, which prompts that prevention and treatment of these chronic diseases may contribute to osteoporosis.
作者
赵蕾
刘学员
陈日超
何杰
卢水焕
廖立
李程
ZHAO Lei LIU Xueyuan CHEN Richao HE Jie LU Shuihuan LIAO Li LI Cheng(Department of Geriatrics, 181th Hospital of PLA, Guangxi Zhuang Autonomous Region, Guilin 541002, China)
出处
《中国医药导报》
CAS
2017年第28期53-56,共4页
China Medical Herald
基金
军队保健专项科研课题(12BJZ14)
广西壮族自治区桂林市科学研究与技术开发计划项目(2016012702-6)
关键词
骨质疏松症
慢性疾病
偏相关分析
Osteoporosis
Chronic diseases
Partial- correlation analysis
