摘要
目的分析2型糖尿病(T2DM)患者阻塞性睡眠呼吸暂停综合征(OSAS)的患病情况及相关因素。方法280例2型糖尿病患者,使用便携式睡眠呼吸监测仪进行OSAS筛查,将患者是否患OSAS分为病例组(212例)和对照组(68例),分析OSAS患病情况及相关因素。结果病例组中,T2DM合并轻度、中度、重度OSAS者分别为17例(8.0%)、30例(14.2%)、165例(77.8%),其BMI水平、合并高血压患病率以及空腹血糖、餐后2 h血糖、糖化血红蛋白(HbA1C)、胰岛素抵抗指数水平均明显高于对照组(P<0.01)。回归分析示HbA1C与OSAS呈正相关(OR=6.31,P<0.01)。结论T2DM患者OSAS的患病率高,且以重度为主,HbA1C是OSAS患病的独立危险因素。
Objective To analyze the prevalence of obstructive sleep apnea syndrome （OSAS） in the patients with Type 2 diabetes mellitus （T2DM） and its related factors. Methods 280 patients with T2DM were selected. OSAS screening was performed using a portable sleep respiration monitor, and the patient were divided into Case Group （212 cases） and Control Group （68 cases） based on whether the patients had OSAS. The prevalence of OSAS and related factors were then analyzed. Results In Case Group, the patients complicated with mild, moderate and severe OSAS were 17 cases （8.0%）, 30 cases （14.2%） and 165 cases （77.8%）, respectively. The BMI level, the prevalence rate of hypertension, fasting blood glucose （FBG）, postprandial 2 h blood glucose, glycosylated hemoglobin （HbA1C） and insulin resistance index （HOME-IR） in Case Group were significantly higher than Control Group （P〈0.01）. Regression analysis showed that HbA1C was positively correlated with OSAS （OR=6.31, P〈0.05）. Conclusion The prevalence of OSAS in the patients with T2DM was high, and HbA1C was an independent risk factor for OSAS.
出处
《广东医科大学学报》
2017年第3期231-233,共3页
Journal of Guangdong Medical University
基金
湛江市科技计划项目(No.2015B01020)
关键词
阻塞性睡眠呼吸暂停
2型糖尿病
血糖
obstructive sleep apnea
Type 2 diabetes mellitus
blood glucose
