摘要
新生儿听力筛查是早期发现听力损失的一种有效手段，但不能发现迟发性听力损失。探讨儿童迟发性听力损失的病因，可为早期检测和发现迟发性听力损失提供临床依据。SLC26A4、线粒体、GJB2等基因突变、前庭导水管扩大、先天性巨细胞病毒感染、体外膜肺氧合及听神经病等是报道较多的迟发性听力损失致病因素。本文拟从遗传因素、内耳畸形、围产期因素、听神经病及原因未明确5个方面，对近年来报道的儿童迟发性听力损失相关因素进行归类、综述及分析。
Newborn hearing screening is an effective method for early detection of hearing loss, however, it is not able to detect delayed-onset hearing loss. By exploring the etiology of delayed-onset hearing loss in children, it can provide a clinical basis for early detection of delayed-onset hearing loss. Mutations in SLC26A4, mitochondrial, GJB2 and other genes, enlarged vestibular aqueduct, congenital cytomegalovirus infection, extracorporeal membrane oxygenation, and auditory neuropathy et al were more commonly reported risk factors. In this paper, the risk factors related to delayed-onset hearing loss, which are divided into 5 categories： genetic mutation, abnormal inner ear malformation, perinatal factors, auditory neuropathy and no identifiable cause, are reviewed and analyzed.
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2017年第10期787-791,共5页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金
首都临床特色应用研究专项基金（Z131107002213123）
北京市自然科学基金（7172052）
关键词
听觉丧失
儿童
Hearing loss
Child
