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龙胆泻肝汤化裁治疗2型糖尿病合并带状疱疹临床观察

Clinical Effect in Patients of Type2 Diabetes Mellitus with Herpes Zoster by Adjusted Longdan Xiegan Decoction
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摘要 目的:观察龙胆泻肝汤化裁治疗2型糖尿病合并带状疱疹临床疗效。方法:符合标准的60例2型糖尿病合并带状疱疹患者随机分为治疗组和对照组,每组各30例,对照组给予盐酸二甲双胍片、瑞格列奈分散片、盐酸伐昔洛韦片;治疗组在对照组基础上加以龙胆泻肝汤化裁治疗,持续治疗并观察1个月,以观察2组空腹血糖、餐后2h血糖、糖化血红蛋白各指标,和疼痛VAS评分、水疱消退、结痂、疼痛缓解时间。结果:2组患者临床疗效比较,观察组、对照组总有效率分别为86.67%、73.77%,有统计学意义(P<0.05);2组患者空腹血糖、餐后2h血糖及糖化血红蛋白比较,治疗前后有统计学意义(P<0.05);2组患者水疱消退、结痂、疼痛开始缓解时间及疼痛VAS评分进行比较,均有统计学意义(P<0.05)。结论:龙胆泻肝汤化裁治疗2型糖尿病合并带状疱疹疗效显著,值得临床推广。 Objective: To observe the clinical effect of Longdan Xiegan decoction in treating type 2 diabetes mellltus with herpes zoster. Methods: 60 patients with type 2 diabetes mellitus complicated with herpes zoster were randomly di- vided into treatment group and control group. The control group was treated with metformin hydrochloride tablets, repa- glinide dispersible tablets and valacyclovir hydrochloride tablets. The treatment group was treated with Longdan Xiegan decoction on the basis of the control group. The treatment was continued for 1 month to observe the two groups of fast- ing blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin, and pain VAS score, Scab, pain relief time. Results: The total effective rate of the observation group and the control group were 86.67% and 73.77% respectively, which were statistically significant (P〈0.05). Blood glucose and glycosylated hemoglobin in 2 groups were significantly higher than those in control group (P〈0.05). 2 groups of patients with blisters subsided, scab, pain began to ease the time and pain VAS score were compared and were statistically significant (P〈0.05). Conclusion: Longdan Xiegan de- coction is effective in the treatment of type 2 diabetes mellitus with herpes zoster. It is worthy to be popularized.
作者 张蔚
出处 《中医药临床杂志》 2017年第9期1488-1491,共4页 Clinical Journal of Traditional Chinese Medicine
基金 宁夏回族自治区重点研发计划(科技惠民)项目(项目编号:2016KJHM109)
关键词 龙胆泻肝汤化裁 2型糖尿病 带状疱疹 临床疗效 Longdan Xiegan decoction, Type2 diabetes mellitus, Herpes zoster, Clinical effect
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