摘要
选择具有不同碳链长度、其它官能团和空间效应的单体,在80℃的二苯醚体系中,采用固定化南极假丝酵母脂肪酶N435催化缩聚,得到一系列的脂肪族聚酯.利用核磁共振氢谱1H NMR表征了所得产物的化学结构,凝胶渗透色谱GPC分析了相对分子质量及分布,并计算了聚合度.研究表明:单体中等链长的1,5-戊二醇Pe DO得到的聚合物的聚合度最高,短碳链的二醇难聚合,长碳链的己二酸二乙酯DEA反应活性高于丁二酸二乙酯DES;单体中官能团的位置、侧基的诱导效应与空间效应都会影响聚合度;单体与酶分子的氢键作用也对聚合度有一定的影响.
In this research,a series of aliphatic polyesters were catalytic condensated by immobilized candida antarctica lipase N435 with different carbon chain length,functional groups and three-dimensional structure monomer in 80 ℃ of diphenyl ether system.Their chemical structure was characterized by1 H NMR,the relative molecular mass and distribution was analysised with GPC,the degree of polymerization was calculated too. The result shows that,the degree of polymerization of the aliphatic polyester which synthesized with the monomer has equal molecular chain length such as 1,5-butyl glycol（Pe DO） was highest,but if synthesized with the monomer has short carbon chain such as diol,the polyester was difficult to synthesis,and the reactivity of the monomer has long carbon chain adipic acid diethyl（DEA） was higher than succinic acid diethyl（DES）. The location of the functional groups in the monomer,induction effect of side chain groups and space effect will affect the degree of polymerization.The hydrogen bonding interaction between monomer and enzyme molecules also affect the degree of polymerization.
出处
《陕西科技大学学报》
CAS
2017年第5期117-121,127,共6页
Journal of Shaanxi University of Science & Technology
基金
陕西省技术转移与重点科技成果推广计划项目(2016CG-10)
陕西科技大学博士科研启动基金项目(BJ15-21)
关键词
脂肪酶N435
脂肪族聚酯
单体结构
聚合度
lipase N435
aliphatic polyesters
monomer structure
degree of polymerization
