摘要
针对交叉设计随机对照试验Cochrane偏倚评估工具2．0版本（RoB2．0）的主要内容进行详细介绍，主要阐述了与平行设计RoB2．0的不同之处，并举例说明交叉设计RoB2．0的使用方法和注意事项。交叉设计RoB2．0针对交叉设计的自身特点，设置了相应的信号问题，为交叉设计试验纳入系统综述进行证据整合提供偏倚风险信息。
This paper introduces the revised Cochrane bias risk assessment tool for individual randomized, cross-over trials （ROB2.0）, comparing ROB2.0 of cross-over design with ROB2.0 of parallel design, and illustrating the application of ROB2.0 for cross-over trials in a published clinical trial. As a comprehensive tool specially designed for cross-over design, it provides more information on risk of bias in systematic reviews for the evidence synthesis.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2017年第10期1436-1440,共5页
Chinese Journal of Epidemiology
关键词
偏倚风险
评估工具
随机对照试验
交叉设计
系统综述
Risk of bias
Tool for assessment
Randomized controlled trial
Cross-over design
Systematic review
