摘要
目的:探讨成人原发性横纹肌肉瘤(rhabdomyosarcoma,RMS)患者的临床及影像学特征。方法:回顾性分析4例经手术病理证实的成人原发性RMS患者的临床资料和影像学表现。结果:4例患者中,病变位于头颈部2例,位于盆腔1例,位于纵隔1例。所有患者均因相应部位肿胀或压迫症状就诊。CT显示病灶为软组织密度肿块,密度欠均匀,周围组织受压推移或侵犯;增强后病灶呈明显不均匀强化,4例患者的病灶内均可见坏死,但未见钙化成分。MRI检查T1WI图像上可见病灶呈等信号,T2WI图像上则以稍高信号为主;增强后呈不均匀持续强化。4例患者的病理组织行免疫组织化学染色,结果肌细胞生成素(Myogenin)均(+),波形蛋白(Vimentin)均(+),1例患者结蛋白Desmin(+)。结论:成人原发性RMS罕见,其在CT及MRI图像上具有一定特征性,结合患者的临床表现进行分析,可提高诊断的准确率。
Objective： To investigate the clinicopathological characteristics, CT and MRI findings of primary rhabdomyosarcoma（RMS）in adults. Methods： Four adult patients with pathologically confirmed RMS admitted to Xinhua Hospital from 2012 to 2016 were enrolled. Results： Two patients had lesions located in head and neck, the other two in anterior chest wall and in pelvic cavity, respectively. RMS tended to be a heterogeneous soft-tissue mass with compression or invasion to surrounding tissue on non-enhanced CT image, which showed heterogeneous enhancement even with strong contrast enhancement in contrast-enhanced CT image. No fat and calcification components were found in all the 4 cases. MR imaging appearance of rhabdomyosarcoma was isointense or minimally hyperintensity in relative to muscle on T1- weighted images and hyperintensity on T2-weighted images. Conclusions： Adult primary rhabdomyosarcoma is rare, which has certain characteristic findings on CT and MRI image. Combined findings on imaging and clinical manifestations, the accuracy of diagnosis could be improved.
出处
《诊断学理论与实践》
2017年第3期301-305,共5页
Journal of Diagnostics Concepts & Practice
基金
上海交通大学医学院科研基金(09XJ21013)
上海市卫生局科研基金(2010029
2010057)
上海市科委科研基金(124119a0300)
上海市教委科研基金(12Y2034)
