摘要
目的:观察健脾化痰祛瘀汤联合常规疗法治疗脑卒中恢复期合并高脂血症患者的临床效果。方法:选取90例痰瘀阻络型脑卒中恢复期合并高脂血症患者,随机分为对照组和观察组各45例。对照组给予常规抗血小板聚集、降脂、稳定斑块、调控血糖、降压及改善心肌供血等治疗,观察组在对照组治疗基础上给予健脾化痰祛瘀汤治疗,2组均治疗4周。观察2组的临床疗效,治疗前后检测总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及全血黏度(高切、低切)、血浆比黏度、红细胞刚性指数。结果:观察组总有效率93.33%,对照组总有效率77.78%,2组比较,差异有统计学意义(P<0.05)。与治疗前比较,2组治疗2周、4周时TG、TC及LDL-C均有不同程度降低,差异均有统计学意义(P<0.05);治疗4周时,2组3项指标水平均低于治疗2周时(P<0.05),观察组3项指标水平均低于对照组(P<0.05)。治疗2周、4周时,2组的全血黏度(高切、低切)、血浆比黏度、红细胞刚性指数均较治疗前降低,差异均有统计学意义(P<0.05);治疗4周时,2组4项指标值均低于治疗2周时(P<0.05),观察组4项指标值均低于对照组(P<0.05)。结论:在常规治疗的基础上加用健脾化痰祛瘀汤治疗痰瘀阻络型脑卒中恢复期合并高脂血症患者可有效缓解症状,调节血脂和改善血液流变学,疗效优于单纯使用西药治疗。
Objective： To observe the clinical effect of JianpiHuatan Quyu tang combined with routine therapy for convalescent stroke with hyperlipidemia. Methods：Divided 90 cases of patients with convalescent stroke with hyperlipidemia of phlegm-stasis blocking collateral type into the control group and the observation group randomly,45 cases in each group.Both groups were given routine treatment such as anti-platelet aggregation, lipid-lowering, plaque stabilization, blood glucose regulation, anti-hypertension, and improvement of myocardial blood supply, while the observation group was additionally given JianpiHuatan Quyu tang. Both groups received treatment for four weeks. Observed the clinical effect and determined total cholesterol（TC）,triglyceride（TG）,lowdensity lipoprotein cholesterol（LDL-C）,whole blood viscosity（in lowshear rate and in high shear rate）,plasma viscosity,and erythrocyte rigidity index in both groups. Results：The total effective rate was 93.33% in the observation group and 77.78% in the control group,the difference being significant（P0.05）. When the two groups received treatment for two weeks and four weeks,TG,TCand LDL-Cin both groups were decreased to different degree, comparing with those before treatment, differences being significant（P 0.05）; when the two groups received treatment for four weeks,levels of the three indexes in both groups were all lower than those after two-week treatment（P0.05）,and levels of three indexes in the observation group were all lower than those in the control group（P0.05）. When the two groups received treatment for two weeks and four weeks,whole blood viscosity（in lowshear rate and in high shear rate）,plasma viscosity,and erythrocyte rigidity indexes in both groups were declined,comparing with those before treatment,differences being significant（P0.05）. When the two groups received treatment for four weeks,levels of four indexes in both groups were all lower than those after two-week treatment（P0.05）,and levels of four indexes in the observation group were all lower than those in the control group（P0.05）. Conclusion：The therapy of JianpiHuatan Quyu tang based on routine therapy for convalescent stroke with hyperlipidemia can effectively improve symptoms,regulate blood lipid and improve hemorheology. Its effect is superior to that of pure western medicine therapy.
出处
《新中医》
CAS
2017年第10期32-34,共3页
New Chinese Medicine
关键词
脑卒中
恢复期
高脂血症
痰瘀阻络型
中西医结合疗法
健脾化痰祛瘀汤
血脂
血液流变学
Stroke
Convalescence
Hyperlipidemia
Phlegm-stasis blocking collateral type
Integrated Chinese andwestern medicine therapy
Jianpi Huatan Quyu tang
Blood lipid
Hemorheology
