摘要
目的探究鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染的临床效果。方法选取2013年10月～2017年3月宁夏医科大学附属吴忠市人民医院神经外科收治的60例脑室外引流术后颅内感染患者,随机抽签分类法分为参照组和研究组,每组30例。参照组采用头孢曲松治疗,研究组采用鞘内注射头孢他啶与头孢曲松治疗,评估2组患者的治疗效果以及不良反应发生率。结果研究组患者的治疗总有效率（96.67%）显著高于参照组（73.33%）;不良反应发生率（3.33%）明显低于参照组（26.66%）,差异均有统计学意义（P〈0.05）。结论采用鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染患者,治疗效果显著,不良反应发生率较低。
Objective To investigate the clinical effect of intrathecal injection of ceftazidime and ceftriaxone in the treatment of intracranial infection after intraventricular drainage.Methods 60 patients with intracranial infection after intraventricular drainage in Wuzhong people＇s hospital from October 2013 to March 2017 were selected and were divided into reference group and study group by random sampling method,with 30 cases in each group.The reference group was treated with ceftriaxone treatment,the study group was treated with intrathecal ceftazidime and ceftriaxone.The therapeutic effect and adverse reaction rate of the two groups were evaluated.Results The total effective rate of the patients in the study group（96.67%） was significantly higher than that in the reference group（73.33 %）,and the adverse reaction rate（3.33%） was significantly lower than that of the reference group（26.66%）,and the difference was statistically significant（P〈0.05）.Conclusion Intrathecal injection of ceftazidime and ceftriaxone in patients with intracranial infection after intraventricular drainage,the treatment effect is obvious,and the incidence of adverse reactions is low,which is worthy of clinical study.
出处
《中国生化药物杂志》
CAS
2017年第10期71-72,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
鞘内注射
头孢他啶
头孢曲松
脑室外引流术
颅内感染
intrathecal injection
ceftazidime
ceftriaxone
intracranial infection
intraventricular drainage
