摘要
目的探讨超声引导神经阻滞麻醉联合丹参注射液对心绞痛疗效及血清相关指标的影响。方法选择2015年7月~2017年2月湖州市中心医院收治的178例心绞痛患者为研究对象,随机分成对照组（n=89）与研究组（n=89）,对照组给予常规西医联合丹参注射液治疗,研究组给予超声引导神经阻滞麻醉联合丹参注射液治疗,对比2组临床疗效、治疗前后同型半胱氨酸（Hcy）、脂联素（APN）、肿瘤坏死因子-α（TNF-α）、超敏C反应蛋白（hs-CRP）、心脏射血分数（EF）及不良反应发生情况。结果对照组治疗总有效率（80.90%）与研究组（95.51%）相比较更低,差异具有统计学意义（P〈0.05）;治疗后,2组Hcy、TNF-α及hs-CRP水平均有所下降,APN、EF水平均有所上升,且研究组变化幅度更大,差异具有统计学意义（P〈0.05）;对照组不良反应发生率与研究组相比（3.37%VS 1.12%）,差异无统计学意义。结论超声引导神经阻滞麻醉联合丹参注射液可有效改心绞痛患者血清相关指标,疗效确切,不良反应少,。
Objective To investigate the efficacy of ultrasound-guided nerve block anesthesia combined with Danshen injection on the treatment of angina and its influence on serum indexes.Methods 178 patients with angina in Huzhou central hospital from July 2015 to February 2017 were randomLy divided into the control group（n=89） and the research group（n=89）.The control group was given routine western medicine combined with Danshen injection,while the research group was treated with ultrasound-guided nerve block anesthesia combined with Danshen injection.The clinical efficacy,homocysteine（Hcy）,adiponectin（APN）,tumor necrosis factor-α（TNF-α）,high-sensitivity C-reactive protein（hsCRP）,ejection fraction（EF） before and after treatment,adverse reactions were compared between the two groups.Results The total effective rate in the control group（80.90%） was lower than that in the control group（95.51%）（P〈0.05）;After treatment,the levels of Hcy,TNF-α,hs-CRP in the two groups increased,and the variety range in the research group was larger（P〈0.05）;The incidence of adverse reactions in the control group and the research group（3.37% VS 1.12%） were compared,there was no statistical difference.Conclusion Ultrasound-guided nerve block anesthesia combined with Danshen injection could effectively improve serum indexes of patients,it has definite efficacy and less adverse reactions,which is worthy of further clinical application and promotion.
出处
《中国生化药物杂志》
CAS
2017年第10期134-136,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
超声
神经阻滞麻醉
丹参注射液
心绞痛
ultrasound
nerve block anesthesia
Danshen injection
angina
