摘要
对于寡转移前列腺癌,越来越多的研究提出行原发灶手术切除可获得相比单纯内分泌治疗更优的生存期和更高的生活质量。近年来,国际指南的更新反映了前列腺癌手术治疗的指征正逐渐放宽,这为寡转移前列腺癌的外科治疗提供了额外的治疗思路。然而,现有研究证据仍限于临床研究阶段,寡转移前列腺癌的影像学诊断尚存在较大发展空间,寡转移前列腺癌的概念与定义尚未得到统一,手术治疗的适应证与治疗时机亦不明确,期待后续前瞻性随机对照研究提供更高等级的临床证据。
As for oligometastatic prostate cancer,agrowing number of studies have indicated that performing radical prostatectomy of the primary tumor may yield better survival and higher quality of life compared with androgen deprivation therapy alone.Update of international guidelines in recent years have reflected a broadened spectrum of indications of radical prostatectomy,providing additional treatment strategies for oligometastatic prostate cancer.However,current evidence is limited to clinical investigations,and novel imaging technology of oligometastatic prostate cancer is still on the rise.Conceptions and definition of oligometastatic prostate cancer itself is still inconsistent,and the indications and timing of performing radical prostatectomy in such case scenario remain unclear.Further prospective randomized controlled clinical studies are required for higher level clinical evidence for future applications.
作者
许传亮
常易凡
孙颖浩
XU Chuanliang CHANG Yi fan SUN Yinghao(Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, 200433, Chin)
出处
《临床泌尿外科杂志》
2017年第9期653-657,共5页
Journal of Clinical Urology
