摘要
目的研究探讨糖尿病心脏自主神经病变与糖尿病末梢神经病变的危险因素。方法随机选取在该院2016年3月—2017年3月期间确诊为2型糖尿病患者342例,根据有无心脏自主神经病变(CAN)与末梢神经病变(DPN)分为CAN组、DPN组两组,比较两组患者的危险因素。结果 CAN共65例,发生率为19.01%;DPN 89例,发生率为26.02%。CAN组与DPM组在病程、FBG、HbA1c以及TC等危险因素上比较差异无统计学意义(P>0.05);但是CAN组患者平均年龄(68.2±5.8)岁、2 hBG(17.5±6.2)mmol/L、TG为(3.0±1.1)mmol/L均要显著高于DPN组(P<0.05);但DPN组的平均VPT为(28.9±8.4)V要显著高于CAN组(P<0.05);另外,两组患者在糖尿病肾病、糖尿病视网膜病变疾病发生率上比较差异无统计学意义(P>0.05);但是CAN组患者的冠心病发病率为96.92%要显著高于DPN组的71.91%(P<0.05)。结论 CAN与DPN两者间在病变发展无明显平行性关系,但两者各有其特征性危险因素,临床上资鉴别。
Objective This paper tr ies to in v es tig ate th e risk factors and co rrelation of d iab e t ic autonomic n eu ro pa th y and diabet ic per ipheral neuropathy. Methods 342 c a se s of type 2 d iab e te s d iagnosed in th is h ospi tal from March 2 0 1 6 to March 2017 were random selected and divided into the CAN group and the DPN group according to whether there were hear t au-tonomic neuropathy （CAN） and per ipheral neuropathy （DPN）. The risk factors of the two groups were compared. Results There were 65 cases with CAN, the incidence rate was 19.01%, and 89 cases with DPN, the incidence rate was 26.02%. There were no signif icant difference of CAN group and DPN group in the course of risk factors in FBG, HbA1c, TC（P〉0.05）; but the average age of pat ients in group CAN was （68.2±5.8）years old, 2 hBG was（17.5±6.2）mmol/L, TG was（3.0±1.1）mmol/L, which were al l higher than DPN group （P〈0.05）; The average VPT in the DPN group was （28.9±8.4）V, signif icantly higher than that of CAN group（P〈0.05）; The two groups of pat ients with diabet ic nephropathy and diabet ic ret inal disease incidence showed no signif icant di fference（P〉0.05）; But the incidence of coronary hear t disease pat ients in the CAN group was 96.92%, signif icantly higher than that of DPN of 71.91%（P〈0.05）. Conclusion T he re is no obvious p a ra l le l re la t io n sh ip b e -tween CAN and DPN in the development of lesions, but both of them have thei r character ist ic r isk factors, which should be figured out in the cl inical practice.
出处
《中外医疗》
2017年第26期16-18,共3页
China & Foreign Medical Treatment
关键词
糖尿病
自主神经
末梢神经
危险因素
Diabetes mel litus
Autonomic nerve
P e r ip h e ra l nerve
Risk factors
