摘要
目的研究产褥期感染患者的临床资料,分析病原菌分布及耐药情况。方法选取2015年1月-2016年12月于医院实施分娩的产妇共2846例,其中产褥期感染者37例。采集临床标本进行细菌培养及药敏试验。结果产褥期感染患者37例,感染率1.30%,共检出病原菌37株,其中革兰阴性菌26株占70.27%,革兰阳性菌11株占29.73%。主要革兰阴性菌对氨苄青霉素出现较强耐药,其中大肠埃希菌对头孢吡肟和左氧氟沙星较为敏感,阴道加德纳菌对左氧氟沙星较为敏感;主要革兰阳性菌对氨苄西林出现较强耐药,其中溶血性链球菌对头孢他啶较为敏感;四种病原菌对哌拉西林舒巴坦、亚胺培南及万古霉素较为敏感或未出现耐药。结论对于产褥期感染患者要早期预防,合理用药,及时处置,本研究药敏结果为产褥期感染患者更换或经验性使用抗菌药物提供一定参考依据。
OBJECTIVE To investigate the clinical data of patients with puerperal infection and analyze the distribution of pathogens and drug resistance.METHODS A total of 2846 puerperant were selected in our hospital from Jan.2015 to Dec.2016,of whom 37 were diagnosed with puerperal infection.Clinical specimens were collected for bacterial culture and susceptibility testing.RESULTS There were 37 cases of puerperal infection,accounting for 1.30%.Totally 37 strains of pathogens were detected,including 26 strains（70.27%）of gram-negative bacteria,and 11 strains（29.73%） of gram-positive bacteria.The main gram-negative bacteria were more resistant to penbritin,among which Escherichia coli was more sensitive to cefepime and levofloxacin,and Gardnerella vaginalis was more sensitive to levofloxacin.The main gram-positive bacteria were more resistant to ampicillin,among which Hemolytic streptococcus was more sensitive to ceftazidime.The four pathogens were more sensitive or had no resistance to piperacillin sulbactam,imipenem and vancomycin.CONCLUSION The main points for the diagnosis and treatment of puerperal infection are early prevention,rational use of drugs and timely treatment.The results of the drug susceptibility provide a reference for the replacement or empiric use of antibiotics in patients with puerperal infection.
作者
常蕊
王楠
高燕云
冯彩霞
李娜
CHANG Rui WANG Nan GAO Yan-yun FENG Cai xia LI Na(Yulin First Hospital of Shaanxi Province, Yulin, Shaanxi 719000, China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第20期4758-4760,共3页
Chinese Journal of Nosocomiology
关键词
产褥期感染
抗菌药物
耐药性
Puerperal infection
Antibiotics
Drug resistance
