摘要
目的了解2012-2016年天津地区住院腹泻儿童的病毒感染情况和流行规律。方法收集天津市儿童医院2012年1月-2016年12月住院的腹泻儿童粪便标本,采用胶体金免疫层析法快速检测轮状病毒(RV)和腺病毒(AdV),采用酶联免疫吸附试验方法(ELISA)进行星状病毒(AstV)抗原检测。结果 11 746份粪便标本中,阳性例数为1 430份,总阳性检出率为12.17%,三种病毒中RV阳性检出率最高(9.46%),其次为AdV(1.83%)、AstV(0.97%);男女阳性检出率差异无统计学意义(χ~2=0.279,P=0.598);各月龄组均能检测到腹泻病毒,其中12~23月龄组的阳性检出率最高(20.02%);RV在12月份阳性检出率最高,其次是11月份,8月份最低;AstV在1月份阳性检出率最高,全年低流行散发;AdV在6月份阳性检出率最高,5~8月呈现一个小高峰。结论 RV是2012-2016年天津地区住院腹泻患儿感染的主要病原之一,秋冬季节为发病高峰。AstV和AdV的感染在婴幼儿腹泻中不容忽视。同时存在一定比例的混合感染。
Objective To investigate the virus infection situation and epidemic law of virus diarrhea among hospitalized children in Tianjin of 2012-2016. Methods Stool samples were collected from hospitalized diarrhea children in Tianjin Children＇s Hospital between Jan 2012 and Dec 2016. To test the rotavirus（RV）and adenovirus（AdV） by using Colloidal Gold Device and test the astrovirus（AstV） by using enzyme-linked immunosorbent Assay（ELISA）. Results Among the 11 746 specimens, 1 430 specimens were positive and total positive rate was 12.17%. The positive rate of RV, AdV and AstV were 9.46%, 1.83%, 0.97%. There was no significant difference in the incidence of virus diarrhea between male and female（χ2=0.279, P=0.598）;The virus could be detected in every months of age group, 12~23 months was the hightest（20.02%）; The hightest detection rate of RV was in Dec, followed by Nov, the lowest in Aug; The hightest detection rate of AstV was in Jan, with low prevalence throughout the year; The hightest detection rate of AdV was in Jun, the peak is from May to Aug. Conclusion RV was a major cause of virus diarrhea between 2012 and 2016 in hospitalized children in Tianjin. The peak of RV infective rate was observed in fall-winter.The pathogenic effect of Ast V and Ad V infection among diarrhea children should not be ignored. At the same time,co-infection were observed in a certain proportion.
作者
马慧
管卫
沈永明
彭林
MA Hui GUAN Wei SHEN Yong-min PENG Lin(Department of Clinical Laboratory, Tianjin Children＇s Hospital, Tianjin 300074, Chin)
出处
《中国城乡企业卫生》
2017年第10期1-3,共3页
Chinese Journal of Urban and Rural Enterprise Hygiene
关键词
腹泻
住院
儿童
轮状病毒
星状病毒
腺病毒
流行病学
Diarrhea
Hospitalized
Children
Rotavirus
Astrovirus
Adenovirus
Epidemiology
