摘要
目的探讨蒲地蓝消炎口服液联合头孢噻肟钠治疗急性肠系膜淋巴结炎的临床疗效。方法选取2016年1月—2017年1月在安康市人民医院进行治疗的88例急性肠系膜淋巴结炎患者为研究对象,根据治疗方案的差别分为对照组(44例)和治疗组(44例)。对照组患者静脉滴注注射用头孢噻肟钠,60~100 mg/(kg·d)加入生理盐水100 m L,2次/d。治疗组在对照组基础上口服蒲地蓝消炎口服液,10 m L/次,3次/d。两组患者均治疗7 d。评价两组患者临床疗效,同时比较治疗前后两组患者临床症状消失时间和血清学指标差异。结果治疗后,对照组总有效率为81.82%,显著低于治疗组的97.73%,两组比较差异具有统计学意义(P<0.05)。治疗后,治疗组患者腹痛、食欲不振、呕吐和腹泻消失时间均显著短于对照组患者,两组比较差异具有统计学意义(P<0.05)。治疗后,两组患者血清C反应蛋白(CRP)和降钙素(PCT)水平均明显降低,同组比较差异具有统计学意义(P<0.05);且治疗组上述指标明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论蒲地蓝消炎口服液联合头孢噻肟钠治疗急性肠系膜淋巴结炎可有效改善患者临床症状,降低机体炎症反应,具有一定的临床推广应用价值。
Objective To investigate the clinical effect of Pudilan Xiaoyan Oral Liquid combined with cefotaxime sodium in treatment of acute mesenteric lymphadenitis. Methods Patients （88 cases） with acute mesenteric lymphadenitis in Ankang People＆#39;s Hospital from January 2016 to January 2017 were divided into control （44 cases） and treatment （44 cases） groups according to different treatments. Patients in the control group were iv administered with Cefotaxime Sodium for injection, 60 — 100 mg/（kg＆#183;d） added into normal saline 100 mL,twice daily.Patients in the treatment group were po administered with Pudilan Xiaoyan Oral Liquid on the basis of the control group, 10 mL/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the differences of the disappearing time of clinical symptoms and serological indexes in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 81.82%, which was significantly lower than 97.73% in the treatment group, and the difference was statistically significant between two groups （P 〈 0.05）. After treatment, the disappearing time of abdominal pain, Anorexia, vomiting and diarrhea in the treatment groups was significantly shorter than that in the control group, and there were differences between two groups （P 〈 0.05）. After treatment, the CRP and PCT in two groups were significantly decreased, and the difference was statistically significant in the same group （P 〈 0.05）. And those indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups （P 〈0.05）. Conclusion Pudilan Xiaoyan Oral Liquid combined with cefotaxime sodium can significantly improve the clinical symptoms and reduce inflammatory reaction in treatment of acute mesenteric lymphadenitis, which has a certain clinical application value.
作者
杨莉萍
周高东
YANG Li-ping ZHOU Gao-dong(Ankang People＇s Hospital, Ankang 725000, Chin)
出处
《现代药物与临床》
CAS
2017年第10期1939-1941,共3页
Drugs & Clinic
