摘要
目的 探讨经皮穿刺瘤体内植入12 5I粒子对肺癌进行近距离放疗的效果 ,并对其并发症进行分析。方法 2 0例周围型肺癌患者 ,在模拟定位机或CT定位下 ,通过穿刺针将12 5I粒子植入到肺癌病灶内 ,通过影像学检查观察疗效 ,并观察其并发症。结果 本组 2 0例患者观察 2个月以上者 18例 ,其中CR 2 7.8% (5 / 18) ,PR 6 6 .7% (12 / 18) ,NC 5 .6 % (1/ 18) ,近期有效率 (CR +PR)高达 94 .4 % (17/ 18)。并发气胸 2 0 % (4/ 2 0 ) ,咯少量血痰 2 5 % (5 / 2 0 ) ,胸膜腔内明显出血 5 % (1/ 2 0 ) ,粒子脱入胸膜腔 5 % (1/2 0 )。结论 经皮穿刺瘤体内植入12 5I粒子治疗肺癌有效率高 。
Objective To evaluate the efficacy and safety of brachytherapy by percutaneous paracentesis implantation of iodine 125 seeds for lung cancer. Methods Twenty patients with peripheral lung cancer were undergone brachytherapy by percutaneous paracentesis implantation of iodine 125 seeds. The effectiveness was evaluated by periodically chest film or CT. The complications were analyzed. Results Eighteen of the twenty patients were observed for more than 2 months. CR, PR and NC were seen in 27.8% (5/18), 66.7% (12/18) and 5.6%(1/18) respectively of the patients. Pneumothorax, hemoptysis and pleural cavity bleeding were seen in 20%(4/20),25%(5/20) and 5%(1/20)respectivly of the patients. Conclusion Brachytherapy by percutaneous paracentesis implantation of iodine 125 seeds for lung cancer is quite effective. The complications are easy to treat.
出处
《重庆医学》
CAS
CSCD
2002年第9期774-775,共2页
Chongqing medicine
