摘要
目的:探讨清石汤联合经皮肾镜取石术(percutaneous nephrolithotomy,PCNL)治疗肾铸型结石的临床疗效及1年复发情况。方法:按随机数字表法将100例肾铸型结石(碎石术前/后结石残留)患者分为观察组与对照组,各50例,观察组采取清石汤联合PCNL治疗,对照组则行单纯PCNL治疗,比较两组临床疗效、并发症及随访1年后两组的复发率。结果:观察组治疗有效率98.00%,显著高于对照组的86.00%,两组比较,差异有统计学意义(P<0.05);观察组结石排净时间、疼痛完全消失时间、住院时间分别为(5.68±1.31)d、(3.45±1.00)d、(5.72±1.22)d,均显著短于对照组的(8.50±2.04)d、(6.20±1.48)d、(9.00±1.46)d,两组比较,差异有统计学意义(P<0.05);两组并发症发生率比较差异无统计学意义(P>0.05);观察组随访6个月、12个月结石复发率分别为2.00%、4.00%,显著低于对照组的14.00%、18.00%,差异有统计学意义(P<0.05)。结论:清石汤联合PCNL治疗肾铸型结石疗效明确,结石排净时间显著短,同时能明显减少术后1年结石复发率。
Objective： To investigate the clinical effect of stone-clearance decoction combined with percutaneous nephrolithotomy（ PCNL） in treating kidney staghorn calculi and the status of 1-year recurrence. Methods： One hundred patients with kidney staghorn calculi（ residual stone before/after lithotripsy） were divided into the observation group and the control group by the random number table method,50 cases in each group. The observation group was treated with stone-clearance decoction and PCNL,and the control group was treated with PCNL alone. The clinical efficacy,complications and 1-year recurrence rate were compared between the two groups. Results： The effective rate of the observation group（ 98. 00%） was significantly higher than that of the control group（ 86. 00%）（ P 〈0. 05）; The time to complete clearance of stones and pain disappearing completely and the reserve time in hospital in observation group [（ 5. 68 ± 1. 31） d,（ 3. 45 ± 1. 00） d,（ 5. 72 ± 1. 33） d] were significantly shorter than those in control group [（ 8. 50 ± 2. 04） d,（ 6. 20 ± 1. 48） d,（ 9. 00 ± 1. 46） d]（ P 〈0. 05）. There was no significant difference in the incidence of complications between the two groups（ P 〉0. 05）. The recurrence rates in the observation group during 6 months and 12 months of follow-up（ 2. 00%,4. 00%） were significantly lower than those in control group（ 14. 00%,18. 00%）（ P 〈0. 05）.Conclusion： The effect of stone-clearance decoction combined with combined with PCNL in the treatment of kidney staghorn calculi is clear. The time to complete clearance of stones is significantly shorter,and it can significantly reduce 1-year recurrence.
出处
《中医学报》
CAS
2017年第10期1994-1996,2021,共4页
Acta Chinese Medicine
基金
十堰市科学技术研究与开发项目计划(ZD2012047)
关键词
肾铸型结石
清石汤
经皮肾镜取石术
中医药治疗
中西医结合
kidney staghorn calculi
stone-clearance decoction
percutaneous nephrolithotomy
TCM therapy
combination of traditional Chinese and Western medicine
