摘要
目的观察硝苯地平联合厄贝沙坦治疗原发性高血压的临床疗效。方法选择2015年6月~2016年6月我院收治的原发性高血压患者60例为研究对象,采取随机数字表法随机分为对照组(n=30,常规治疗+硝苯地平)和观察组(n=30,常规治疗+硝苯地平联合厄贝沙坦治疗),治疗8周后对临床疗效及血压控制情况应用统计学方法进行比较分析。结果治疗后,观察组的临床总有效率为96.7%,显著高于对照组,组间比较差异有统计学意义(χ2=6.83,P<0.05)。两组治疗后SBP、DBP水平均较治疗前显著降低,差异有统计学意义(P<0.05);治疗后观察组SBP水平为(120.9±18.7)mm Hg、DBP水平为(71.5±13.6)mm Hg,分别显著低于对照组,组间比较,差异有统计学意义(P<0.05)。结论原发性高血压在常规治疗的基础上予以硝苯地平联合厄贝沙坦治疗,能有效提高临床治疗效果,降低血压水平,值得临床广泛推广和应用。
Objective To observe the clinical effect of nifedipine combined with irbesartan in the treatment of essential hypertension. Methods A total of 60 cases of essential hypertension in our hospital from June 2015 to June 2016 were selected as the study subjects. The patients were randomly assigned to the control group（n=30, conventional therapy＋nifedipine） and observation group（n=30, conventional treatment ＋nifedipine combined with irbesartan） according to the random number table method. After 8 weeks of treatment, the clinical efficacy and blood pressure control were analyzed and compared via statistical method. Results After treatment, the total clinical effective rate was 96.7% in the observation group, which was significantly higher than that in the control group, there was significant difference between the two groups（χ2=6.83, P〈0.05）. The levels of SBP and DBP in the two groups after treatment were significantly lower than those before treatment, and the differences were statistically significant（ P〈0.05）; after treatment, the SBP level was（120.9±18.7） mm Hg, and DBP level was（71.5±13.6） mm Hg in the observation group, the levels were significantly lower than those in the control group, the differences between the two groups were statistically significant（P〈0.05）. Conclusion On the basis of the conventional treatment, nifedipine combined with irbesartan in the treatment of essential hypertension can effectively improve the clinical therapeutic effect and lower the blood pressure level, which is worthy of being widely popularized and applied in clinical practice.
出处
《中国现代医生》
2017年第28期36-38,共3页
China Modern Doctor
