摘要
目的探讨淀粉酶、脂肪酶和C反应蛋白联合检测对急性胰腺炎(AP)的早期诊断价值,以及对病情严重程度的评估价值。方法选取2013年8月至2015年9月该院收治的AP患者60例作为AP组,并选取同期非急性胰腺炎急腹症(NAA)患者32例和健康体检者50例分别作为NAA组和健康组。检测各组血清淀粉酶(AMY)、脂肪酶(LPS)和C反应蛋白(CRP)水平,并进行比较分析。结果 AP组血清AMY、LPS水平分别为(791.9±444.1)、(443.2±119.2)U/L,均高于NAA组与健康组,差异有统计学意义(P<0.05)。AP组血清CRP水平为(82.3±37.3)mg/L,与NAA组比较差异无统计学意义(P>0.05)。3种指标联合检测用于AP早期诊断的灵敏度、特异度和准确度分别为81.4%、100.0%和90.7%,均高于各指标单独检测,差异有统计学意义(P<0.05)。结论血清AMY、LPS和CRP检测有助于急性胰腺炎的早期诊断和病情严重程度的评估。
Objective To evaluate the early diagnostic value of combined detection of amylase（AMY）,lipase（LPS）and C-reactive protein（CRP）for acute pancreatitis（AP）and its evaluation value on the disease severity.Methods 60 cases of AP in the hospital from August 2013 to September 2015 were selected as the AP group,meanwhile 32 cases of non-AP acute abdomen（NAA）and50 cases undergoing healthy physical examination were selected as the NAA group and healthy group respectively.The levels of serum CRP,AMY and LPS in each group were detected and the detection results were performed the comparative analysis.ResultsThe serum AMP and LPS in the AP group were（791.9±444.1）and（443.2±119.2）U/L respectively,which were significantly higher than those in the NAA group and healthy group,the difference was statistically significant（P0.05）.The CRP level in the AP group was（82.3±37.3）mg/L,which showed no statistical difference compared with the NAA group（P0.05）.The sensitivity,specificity and accuracy of 3-indicator combined detection for early diagnosis of AP were 81.4%,100.0% and 90.7%,which were higher than those in the single indicator detection,the difference was statistically significant（P0.05）.Conclusion The combined detection of AMY,LPS and CRP is conducive to early diagnosis of AP and evaluation of disease severity.
出处
《国际检验医学杂志》
CAS
2017年第21期2979-2981,共3页
International Journal of Laboratory Medicine
