摘要
目的建立测定小儿健脾贴膏中丁香酚、异龙脑和龙脑3种成分含量的一测多评法。方法采用GC法,以萘为内标物、丁香酚为内参物,建立该成分与异龙脑和龙脑的相对校正因子,用该校正因子进行3种有效成分的含量测定,与内标法计算值进行比较。结果一测多评法计算值和内标法测得的异龙脑和龙脑的百分含量相对误差均小于2.0%。结论 GC一测多评法用于小儿健脾贴膏中丁香酚、异龙脑和龙脑3个有效成分的含量测定可行、准确。
Objective To establish a quantitative method by GC with quantitative analysis of multi-components by single-marker（QAMS）for the simultaneous determination of the content of eugenol,isoborneol and borneol in Xiaoerjianpi Plaster.Methods GC was used and naphthalene was served as the internal standard.Eugenol was used as the index,the relative correction factors（RCF）were used to calculate the contents of isoborneol,borneol,and the calculated values were compared with that of internal standard method.Results For isoborneol and borneol,the relative error of the calculated value of QAMS and the measured value of internal standard method was less than 2.0%.Conclusion The QAMS method is feasible and credible for the simultaneous determination of the 3 components in Xiaoerjianpi Plaster.
出处
《西北药学杂志》
CAS
2017年第6期750-754,共5页
Northwest Pharmaceutical Journal
关键词
丁香酚
异龙脑
龙脑
小儿健脾贴膏
GC
一测多评法
含量测定
eugenol
isoborneol
borneol
Xiaoerjianpi Plaster
GC
quantitative analysis of multi-components by single marker
con- tent determination
