摘要
湿热证是多种重大疾病常见证候,古今文献报道众多,多集中于疾病诊疗和单一疾病的关联分析,缺少对湿热证的证本质、分布规律、辨证标准研究等。本研究系统梳理已发表的现代证候文献,以"湿热证"+"临床研究or流行病学"为关键词,检索CNKI、万方、VIP、PUBMED等数据库,采用改良Jadad量表和质量指数量表分别评价和筛选全部文献,最终纳入193篇。对所选文献进行统计分析,发现:(1)湿热证临床研究关注度日益提高,发表文献增量明显;(2)湿热证是多种临床重大疾病的常见证候,以消化病、代谢病、泌尿系统疾病最为突出,但多为单病研究,罕见"异病同证"研究;(3)湿热证地区分布广泛,但病源区域却较为集中,多为经济发达区域,缺少全国性的协同攻关。因此,亟需系统开展湿热证的证本质研究,特别是湿热证在常见重大慢性疾病如糖尿病及其相关疾病、慢性肝病、慢性胃炎、肾炎等疾病中的共性研究。同时,需要开展大样本、多区域流行病学调查和临床研究,并建立湿热证现代辨识标准。
Damp-heat syndrome is a common syndrome of many serious diseases. There are many ancient and modern literature reports about damp-heat syndrome, which mainly focus on the diagnosis and treatment of diseases and the association analysis of single diseases, lack of the syndrome essence, distribution and the standard of syndrome differentiation. This study systematically combed published reports about modern syndromes, and searched the data in CNKI, WANFANG, VIP and PUBMED, with the ＂damp-heat syndrome＂ ＋ ＂clinical research or epidemiology＂ as key words. All the reports were evaluated and screened by using the modified Jadad scale and the quality index scale, and finally 193 articles were included. The statistical analysis of the selected reports showed that： （ 1） the clinical research of damp-heat syndrome had got more attention, with increased numbers of published papers; （ 2） damp-heat syndrome was a common syndrome of many serious diseases, the most prominent of which were digestive diseases, metabolic diseases and urinary system diseases; （ 3） damp-heat syndrome was widely distributed, but the source region was concentrated on the economically developed areas, lack of national collaborative research. Therefore, it is urgent to systematically carry out the research on the essence of damp-heat syndrome, especially the common research on the damp-heat syndrome of common chronic diseases such as diabetes mellitus and its related diseases, chronic liver disease, chronic gastritis and nephritis, et al. At the same time, it is necessary to carry out large sample, multi-regional epidemiological investigation and clinical research, and establish a modern identification standard of damp-heat syndrome.
出处
《广东药科大学学报》
CAS
2017年第5期654-658,共5页
Journal of Guangdong Pharmaceutical University
基金
国家自然科学基金重点项目(81530102)
广东省科技厅国际合作基地建设
代谢病中西医结合防治国际合作基地建设项目(2016B050501003)
关键词
湿热证
文献研究
证本质
辨证标准
damp-heat syndrome
literature research
syndrome essence
the standard of syndrome differentiation
