摘要
胃癌是我国发病率极高的恶性肿瘤,临床可采用手术治疗、化疗、免疫治疗、中医中药治疗等方法。中药活性成分为天然提取而来,因其副作用小、多靶点控制肿瘤、提高患者生存质量等优点,逐步引起国内外学者的关注。中药活性成分诱导胃癌细胞凋亡主要通过调控相关基因表达、阻滞细胞周期、调控相关通路来实现的。本文总结了近年来中药活性成分在诱导胃癌细胞凋亡方面的研究,以期为中药提取物临床应用于胃癌治疗提供帮助。
Gastric cancer is a malignant tumor with high incidence in China, it can be treated by surgery, chemotherapy,immunotherapy, traditional Chinese medicine treatment and so on. The active ingredients of traditional Chinese medicine are extracted from nature, because of its small side effects, multi target control of tumor, and improvement of the quality of life of patients, gradually attract the attention of scholars both at home and abroad. The apoptosis of gastric cancer cells induced by active ingredients of traditional Chinese medicine mainly depend on the regulation of related gene expression, block cell cycle, and regulation of related pathways.In this paper, we summarized recent studies on the active components of traditional Chinese medicine in inducing apoptosis of gastric cancer cells, in order to provide the help for the clinical application of Chinese medicine extract in the treatment of gastric cancer.
出处
《中国现代医生》
2017年第29期165-168,共4页
China Modern Doctor
关键词
胃癌
中药
细胞凋亡
基因
Gastric cancer
Traditional Chinese medicine
Apoptosis
Gene
