摘要
目的研究老年绝经妇女补充钙和维生素D对体成分和骨矿物水平的影响。方法选取2013年3月至2015年3月到该院检查的老年绝经妇女300例,随机分为对照组和试验组,对照组患者连续服用钙剂1年,试验组患者连续服用钙剂及维生素D 1年,比较干预前后2组患者身体中骨矿物水平和体成分的变化。结果 25-羟基维生素D[25(OH)D]水平与身高、体质量无关,干预前后比较差异无统计学意义(P>0.05);全身体质量指数(BMI)和体脂百分比(PBF)水平随25(OH)D水平的升高而降低,差异有统计学意义(P<0.05);25(OH)D水平对全身体脂(BF)和瘦体质量(LBM)水平没有影响,干预前后比较差异无统计学意义(P>0.05)。血清25(OH)D水平与全身、股骨颈、腹中部等部位的骨密度(BMD)呈正相关关系,但25(OH)D水平始终与腰椎无关。结论同时对老年绝经妇女补充钙和维生素D,在控制体质量、维持骨量等方面优于单纯补钙,且能有效地预防骨量流失、骨质疏松等相关疾病。
ObjectiveTo study the effect of calcium and vitamin D supplementation on body compositions and bone mineral level in elderly menopausal women.MethodsThree hundreds elderly menopausal women in this hospital from March 2013 to March 2015 were randomly selected and randomly divided into the control group and experimental group.The control group took oral calcium for 1 year.The experimental group took oral calcium and vitamin D for 1 year.The bone mineral content and body compositions before and after intervention were compared between the two groups.ResultsThere was no correlation between the 25（OH）D level with body height and body mass,there was no statistically significant difference between before and after intervention（P〉0.05）.However,the levels of BMI and percentage of body fat（PBF）were decreased with the 25（OH）D level increase,the difference was statistically significant（P〈0.05）.The 25（OH）D level had no effect on body fat（BF）and lean body mass（LBM）,there was no statistically significant difference between before and after intervention（P〉0.05）.Serum 25（OH）D level was positively correlated with BMD in the whole body,femoral neck and middle part of the abdomen,but the 25（OH）D level had no association with lumbar spine.ConclusionCalcium supplementation and vitamin D supplementation in elderly menopausal women are more effective in controlling body weight and maintaining bone mass than simple calcium supplementation,moreover which can effectively prevent bone loss,osteoporosis and other related diseases.
出处
《检验医学与临床》
CAS
2017年第22期3305-3308,共4页
Laboratory Medicine and Clinic
基金
青海省2015年卫生计生指导性科研课题资助项目(NO.15)
