摘要
目的研究全胃切除食管-空肠roux-en-y吻合术治疗进展期近端胃癌的疗效。方法回顾性分析2013年2月—2016年6月在该院就诊的104例进展期近端胃癌患者临床资料,根据手术方式不同分组,对照组患者行近端胃切除胃-食管吻合术;观察组患者行全胃切除食管-空肠roux-en-y吻合术,对比两组患者的治疗效果。结果观察组患者的手术时间长[(219.2±15.4)min vs(193.6±12.6)min],但淋巴结清扫数目比对照组多[(23.4±2.1)个vs(16.8±1.6)个](P<0.01);在住院时间[(17.2±2.5)d vs(17.5±2.3)d]、术后并发症发生率(15.38%vs 17.31%)、术后6个月Visick分级指数、1年生存率(96.15%vs 92.31%)上两组差异无统计学意义(P>0.05)。结论全胃切除食管-空肠roux-en-y吻合术治疗进展期近端胃癌虽然手术时间略长,但是淋巴结清扫数目多,有助于预防肿瘤的复发,5年生存率更高;且全胃切除对患者的生活质量影响不大,值得推广。
Objective To research the curative effect of total gastrectomy-jejunum roux-en-y anastomosis in treatment of advanced proximal gastric cancer. Methods 104 cases of patients with advanced proximal gastric cancer diagnosed in our hospital from February 2013 to June 2016 were selected and divided into two groups according to different operation methods, the control group were treated with Proximal gastrectomy with gastro esophageal anastomosis, while the observation group were treated with Total Gastrectomy-jejunum roux-en-y anastomosis, and the treatment effect was compared between the two groups. Results The operation time in the observation group was longer than that in the control group[（219.2±15.4）min vs（193.6±12.6）min], and the lymph node dissection number were more than that in the control group,（23.4±2.1 vs 16.8±1.6）（P〈0.05）, and the length of stay, incidence rate of postoperative complications, Visick grading indexes after 6-month operation, 1-year survival rate between the two groups were not statistically significant,[（17.2±2.5）d vs（17.5±2.3）d],（15.38% vs 17.31%）,（96.15% vs 92.31%）]（P〉0.05）. Conclusion The operation time of Total Gastrectomy-jejunum roux-en-y anastomosis in treatment of advanced proximal gastric cancer is long, but the lymph node dissection number is more, and 5-year survival rate is higher, which contributes to preventing the tumor recurrence, and the effect of total gastrectomy on the quality of life is not big, and it is worth promotion.
出处
《系统医学》
2017年第16期90-92,107,共4页
Systems Medicine
关键词
近端胃癌
全胃切除
近端胃切除
食管空肠roux-en-y吻合
Proximal gastric cancer
Total Gastrectomy
Proximal gastrectomy
Gastrectomy-jejunum roux-en-y anastomosis
