摘要
高通量代谢组学近年来发展十分迅速,并在药用植物的研究中得到了广泛的应用。目前,它主要被用于通过指纹图谱对药用植物进行质量控制,比较基因改造后药用植物的代谢差异,监测不同环境对药用植物的代谢变化以及研究药用植物基因的功能。高通量代谢组学具有良好的前景,但也存在对仪器要求较高及数据整合烦琐等问题,限制其更好的推广和应用。随着科学技术的发展及仪器设备联用的普及,高通量代谢组学必将在药用植物的研究中发挥不可替代的作用。
High-throughput metabolomics have developed very rapidly in recent years and been widely used in medicinal plants research . At present, high-throughput metabolomics mainly applied in the following areas , quality control of medicinal plants by fingerprints,metabolites difference comparison before and after genetic engineering,monitoring metabolites change in different environment and gene function study . High-throughput metabolomics have a great future , but still have some challen-ges ,such as the requirements for more sophisticated equipment and complexity of data integration . With the advancement of science and technology, high-throughput metabolomics will be an irreplaceable tool for the research of medicinal plants .
作者
郭志英
周正
谭何新
张磊
刁勇
GUO Zhiying;ZHOU Zheng;TAN Hexin;ZHANG Lei;DIAO Yong(School of Biomedical Science ,Huaqiao Universi-ty ,Quanzhou ,362021 ,China;Department of Pharmaceutical Botany ,School of Pharmacy ,Second Military Medical University , Shanghai 200433 ,China)
出处
《药学实践杂志》
CAS
2017年第6期499-503,共5页
Journal of Pharmaceutical Practice
关键词
高通量代谢组学
药用植物
质量控制
数据整合
high-throughput metabolomics
medicinal plants
quality control
data integration
