摘要
目的:观察川芎茶调散治疗过敏性结膜炎患者的临床疗效及其安全性。方法:将收治的138例患者按照随机数字表法分为2组各69例。对照组予0.1%盐酸奥洛他定滴眼液。观察组在对照组治疗方案的基础上加用川芎茶调散治疗。2组疗程均为14天。比较2组临床疗效,治疗前后主要症状、体征评分变化,及安全性评价。结果:2组临床疗效比较,总有效率观察组92.75%,对照组76.81%,2组临床疗效比较,差异有统计学意义(P<0.05)。治疗后,2组患者眼痒、流泪、眼异物感评分降低,分别与治疗前比较,差异均有统计学意义(P<0.05);治疗后,观察组患者眼痒、流泪、眼异物感评分均低于对照组,2组间比较,差异均有统计学意义(P<0.05)。治疗后,2组患者上睑结膜乳头、下睑结膜乳头、分泌物评分均降低,差异均有统计学意义(P<0.05);治疗后,观察组患者上睑结膜乳头、下睑结膜乳头、分泌物评分均低于对照组,2组间比较,差异均有统计学意义(P<0.05)。2组用药期间均未出现严重不良反应。结论:川芎茶调散治疗过敏性结膜炎患者临床疗效良好,且用药安全性良好。
Adjective. To observe clinical effect and safety of Chuanxiong Chatiao powder in treating patients with allergic conjunctivitis. Methods. Divided 138 patients in our hospital into two group being 69 cases in each, according to the random table mathod. The control group was given 0.1% olopatadine hydrochloride eye drops. The observation group was given Chuanxiong Chatiao powder, based on the treatment of the control group. Course of the two groups lasted for 14 days. Compared clinical effect of the two groups, change of major symptoms before and after treatment, score of the body sign and evaluated the safety. Results： Compared clinical effect of the two groups, the total effective rate was 92.75% in the observation group and was 76.81% in the control group, the difference being significant（P 〈 0.05）. After treatment, score of itching in the eyes, lacrimation and foreign body sensation of the patients in both groups were all lower than those before treatment, differences being significant（P〈0.05）; After treatment, score of itching in the eyes, lacrimation and foreign body sensation of the patients in the observation group were all lower than that of the control group, differences being significant （P 〈0.05）. After treatment, score of conjunctival papilloma of upper eyelid and lower eyelid, secretion of the both groups were all lower than those before treatment, the difference being significant（P〈 0.05）. After treatment, score of conjunctival papilloma of upper eyelid and lower eyelid, secretion of the observation group were all lower than that of the control group, differences being significant （P 〈0.05）. There was no severe adverse reaction during taking medication. Conclusion. Chuanxiong Chatiao powder has good clinical efficacy and high safety in treating allergic conjunctivitis.
出处
《新中医》
CAS
2017年第11期87-90,共4页
New Chinese Medicine
关键词
过敏性结膜炎
中西医结合疗法
0.1%盐酸奥洛他定滴眼液
川芎茶调散
安全性
Allergic conjunctivitis
Integrated Chinese and western medicine
0.1% olopatadine hydrochloride eye drops
Chuanxiong Chatiao powder
Safety
