摘要
目的:观察总结洪霞教授运用扶土抑木理论治疗脾虚肝亢型小儿多发性抽动症临床经验及具体作用机制研究。方法:选取2015年8月~2017年1月来我院就诊的门诊及住院小儿多发性多动症患儿71例,随机分为对照组和观察组,对照组39例,观察组42例。对照组患者给予口服泰必利片,4周1疗程,连续治疗3疗程;观察组患者给予院内自拟方治疗,每日1剂,分早晚2次温服,4周1疗程,连续治疗3疗程。观察治疗前后2组患者血清中5-羟色胺(5-HT)、多巴胺(DA)的含量,以及治疗后临床疗效,观察2组患儿的不良反应及随访后的复发率。结果:2组患儿经过治疗2个疗程之后血清中的5-HT、DA的水平均明显下降(P<0.05);对照组的总有效率为74.4%,而观察组的治疗总有效率为90.5%。结论:扶土抑木理论论治脾虚肝亢型小儿抽动症疗效确切,不良反应发生率较小,且复发率较低。
Objective：To summarize the clinical experience and specific mechanism of professor HONG Xia’s ＂inhibiting wood and strengthening earth＂ in the treatment of infantile tourette syndrome with spleen-deficiency and liver-Qi hyperactivity syndrome.Methods：From August 2015 to January 2017,71 outpatients and hospitalized children with multiple ADHD in our hospital were randomly divided into controlled group and observation group,39 cases in the controlled group,and 42 cases in the observation group.The controlled group were treated with Tiapridal Tablet orally for 4 weeks,1 course of treatment,continuously treating 3 courses.The observation group was treated with self-made hospital decoction,1 day and the 2 day,4 week,1 course of treatment,continuous treatment of 3 courses.The serum levels of 5-HT（5-HT）,dobaamine（DA） and the clinical efficacy were observed before and after treatment in 2 groups.The adverse reactions of the 2 groups and the recurrence rate after follow-up were observed.Results：After 2 courses of treatment,the serum levels of 5-HT and DA decreased significantly in the 2 groups（P〈0.05）.The total effective rate of the controlled group was 74.4%,while the total effective rate of the observation group was 90.5%.Conclusion：The theory of ＂inhibiting wood and strengthening earth＂ is effective in treating infantile Tourette syndrome with spleen-deficiency and liver-hyperactivity syndrome.The incidence of adverse reactions is small and the recurrence rate is low.
作者
佟丹
张文华
TONG Dan;ZHANG Wenhua(Department of Pediatrics, Traditional Chinesi Medicine Hospital of Ankang City, Ankang Shaanxi 725000, China;Department of Pediatrics, Traditional Chinese Medicine Hospital of Ankang City Ankang Shaanxi 725000, China)
出处
《四川中医》
2017年第10期130-132,共3页
Journal of Sichuan of Traditional Chinese Medicine
关键词
抑木扶土
小儿抽动症
5-HT
脾虚肝亢型
Inhibiting wood and strengthening earth
Infantile Tourette syndrome
5-HT
Spleen-deficiency and liver-hyperactivity syndrome
