摘要
免疫组织化学是淋巴组织增生性病变病理诊断与鉴别诊断不可缺少的方法之一,但是必须正确应用和评估其免疫表型结果.重点应注意下列几点：（1）同类抗体的合理配伍;（2）免疫表型假阳性与假阴性的识别;（3）免疫表型阳性定位正确性的识别;（4）抗体非特异性的识别;（5）瘤细胞与反应性细胞免疫表型的识别;（6）免疫表型在淋巴组织增生性病变良恶性鉴别诊断中的正确应用.强调免疫组织化学技术须与其他淋巴组织增生性病变诊断要素相结合才能获得满意的结果.
The immunohistochemistry is an useful method for pathological diagnosis and differential diagnosis of lymphoproliferative lesions,but it must be used correctly and its immunophenotypic results should be evaluated. The following points should be paid attention： （1） Similar antibodies must be reasonable compatibility; （2） the pseudo-positive and pseudo-negative of immunophenotype must be distinguished; （3） the immunophenotypica site must be distinguished; （4） the specify of the antibody expression must be distinguished; （5） the immunophenotype in the tumor cells or reactive cells must be distinguished; （6） the immunophenotype must be used correctly in differential diagnosis between the benign and malignant of hyperplastic lymphoid tissues. The author emphasizes that immunohistochemical techniques need to be combined with other diagnostic features of lymphoproliferative lesions,in order to obtain satisfactory results.
出处
《白血病．淋巴瘤》
CAS
2017年第10期629-630,640,共3页
Journal of Leukemia & Lymphoma
关键词
免疫组织化学
淋巴组织增生性病变
病理
临床
诊断
Immunohistochemistry
Lymphoproliferative lesions
Pathology
clinical
Diagnosis
