摘要
目的分析脑梗死患者Ⅱ级预防的依从性与认知功能、颈动脉斑块、Hcy、C-反应蛋白的相互关系。方法选取2013年2月至2015年2月期间于在本院住院的共500例脑血管病患者中符合条件的122例患者为研究对象,采用随机数字表法将60例加用盐酸多奈哌齐的脑梗死患者作为治疗组,并以同期住院的患者62例作为对照组。两组分别检测MMSE、颈动脉彩超、检测血清Hcy及CRP水平以及WML,并进行比较分析。结果两组患者血清Hcy及CRP水平均有增高,治疗组患者治疗后Hcy水平较对照组明显下降(P<0.05)。治疗组认知水平好转比对照组更为显著(P均<0.05),差异有显著性,P<0.01。结论认知功能损害、颈动脉不稳定斑块、CRP、Hcy及WML与脑梗死患者Ⅱ级预防依从性有关,应该重视相关因素检测及干预。
Objective To analyze the compliance to class Ⅱ prevention for patients with cerebral infarction diseases and its correlation with cognition function and other factors. Methods During February 2013 and February 2015,a total of 122 eligible patients in our hospital were chose from 500 cases of cerebrovascular disease patients as the research object,using random number table method,60 cases of cerebral infarction patients received donepezil were chosen as the treatment group,and a cohort of 62 patients were chose as control group. MMSE,carotid artery ultrasonography,Hcy and serum level of CRP and WML of the two groups were detected respectively,and comparative analyzed.Results Two groups of patients with serum Hcy and CRP levels increased,the level of Hcy in treatment group decreased significantly after treatment compared with the control group（ P〈0. 05）. The improvement of cognitive level in treatment group was more significant than the control group（ P〈0.05）.Conclusions The cognitive function injury,unstable carotid plaque,serum Hcy and CRP were important risk factors of compliance to class Ⅱ prevention for patients with cerebral infarction diseases,we should focus on the detection of risk factors and prevention of it.
出处
《齐齐哈尔医学院学报》
2017年第17期2017-2019,共3页
Journal of Qiqihar Medical University
关键词
脑梗死
Ⅱ级预防
依从性
认知功能
Cerebral infarction
Class Ⅱ prevention
Patient compliance
Cognitive function
