摘要
背景与目的:脑瘤是仅次于脑卒中的主要致死性神经疾病。该研究旨在阐明上海市原卢湾区2004—2011年脑瘤的发病率和死亡率。方法:系统整理2004年1月—2011年12月上海市肿瘤登记报告中上海市原卢湾区户籍人群脑瘤发病和死亡资料并进行统计分析,计算脑瘤发病率及死亡率,用2000年全国第5次人口普查的标准人口年龄构成进行标化。对发病率和死亡率进行趋势分析。结果:上海市卢湾区2004—2011年共报告脑瘤新发病例292例,占同期全区恶性肿瘤的2.80%。死亡病例共148例。男女性发病率与死亡率差异无统计学意义。2004—2011年男女性脑瘤的发病率和死亡率均有一定波动,但差异无统计学意义。结论:2004—2011年上海市卢湾区户籍人群脑瘤的发病和死亡几乎在各年龄段均有发生。研究脑瘤的流行病学特征和发生、发展机制对其预防、治疗及改善预后有显著意义。
Background and purpose： Brain tumor is a major fatal neurological disease after cerebral apoplexy. The current study aimed to analyze the incidence and mortality of brain tumors among residents in former Luwan District of Shanghai from Jan. 2004 to Dec. 2011. Methods： The data of brain tumors in permanent residents of former Luwan District were collected from the database of cancer registration and management system in Shanghai. The incidence and mortality of brain tumors were calculated. The rates were standardized by the demographic compo- sition developed in the Fifth Nationwide Census in the year 2000. The temporal trend in the incidence and mortality of brain tumors was assessed. Results： A total of 292 cases of brain tumors were diagnosed from Jan. 2004 to Dec. 2011, accounting for 2.80% of the total patients with malignant diseases. A total of 148 cases died of brain tumors during this period. There were no significant differences in brain tumor incidence and mortality between males and females. There were some fluctuations in the incidence and mortality rates of brain tumors for both males and females from 2004 to 2011. Conclusion： The occurrence of brain tumors and death happened in almost all age categories among permanent residents in former Luwan District of Shanghai from 2004 to 2011. Studying the epidemiology and mechanisms of brain tumor occurrence and progression can aid in the development of effective prevention and treatment strategies, andimprove prognosis.
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2017年第10期789-794,共6页
China Oncology
基金
黄浦区优秀学科带头人项目(HPXD-05)
关键词
脑瘤
发病率
死亡率
生命统计
Brain tumors
Incidence
Mortality
Vital statistics
