摘要
食管癌发病机制复杂,与饮食、遗传、环境等诸多因素有关。近年来,随着宏基因组学研究的兴起及高通量测序技术的发展,食管微生态的研究已经成为研究食管癌病因学的热点之一。目前已经有不少的研究探讨了食管微生态与食管癌发生发展的关系及其发挥的作用与可能机制。该文就相关研究进展进行综述。
The pathogenesis of esophageal cancer is complex,in which genetic,dietary,environment and other factors may be involved. In recent years,with the rising of metagenomies and the development of high-throughput sequencing technique,microbiota have become a hotspot in the study of the etiology of esophageal cancer. This article reviews the research progress on the relationship between esophageal microbiota and the development and progression of esophageal carcinoma, and the related mechanisms.
出处
《中国肿瘤》
CAS
CSCD
2017年第11期899-903,共5页
China Cancer
基金
"十三五"国家重点研发计划项目(重大慢性非传染性疾病防控研究)(2016YFC1302800)
中国医学科学院医学与健康科技创新工程项目(2016-I2M-1-001)
关键词
食管癌
微生态
宏基因组
病因学
机制
esophageal carcinoma
microbiota
metagenomics
etiology
mechanism
