摘要
目的对新生儿肺透明膜病(HMD)的危险因素进行分析,为新生儿HMD的防治提供理论依据。方法研究对象选择温州医科大学附属第一医院2015年12月—2016年12月期间收治的80例新生儿HMD患儿以及同时期未患HMD的正常新生儿80例,分别设为观察组与对照组。通过临床检查以及妊娠期检查资料回顾性分析研究HMD的危险因素,并采用Logistic回归分析进行多因素分析,分析HMD的独立危险因素。结果 HMD的危险因素有为胎盘早剥[OR=8.564,95%CI(6.431,39.542)]、母亲糖尿病[OR=9.431,95%CI(4.153,36.431)]、宫内窘迫[OR=11.332,95%CI(1.123,38.457)]、多胎妊娠[OR=7.441,95%CI(2.546,33.431)]、前置胎盘[OR=10.431,95%CI(6.132,23.323)]。结论新生儿HMD的危险因素包括胎盘早剥、母亲糖尿病、宫内窘迫、多胎妊娠、前置胎盘,预防HMD需要加强分娩监护以及高危妊娠的干预治疗,积极预防相关危险因素,降低HMD发生率及死亡率。
Objective To analyze the risk factors for hyaline membrane disease( HMD) in newborn baby in order to theoretical basis for prevention and treatment of neonatal HMD. Methods 80 newborn children with HMD in the First Affiliated Hospital of Wenzhou Medical University from December 2015 to December 2016 year were selected as the observation group and 80 newborn children without HMD were selected as the control group at the same period. The risk factors of HMD were retrospectively analyzed by clinical examination and pregnancy examination data. The independent risk factors of HMD were analyzed by Logistic regression analysis. Results The risk factors of HMD in newborn children included placental abruption[OR = 8. 564,95% CI( 6. 431,39. 542) ],maternal diabetes [OR = 9. 431,95% CI( 4. 153,36. 431) ],fetal distress[OR = 11. 332,95% CI( 1. 123,38. 457) ],multiple pregnancy [OR = 7. 441,95% CI( 2. 546,33. 431) ]and placenta previa [OR = 10. 431,95% CI( 6. 132,23. 323) ]. Conclusion The risk factors of Hyaline Membrane Disease in Newborn children include placental abruption,mother diabetes,fetal distress,multiple pregnancy and placenta previa. The prevention of HMD in newborn children need to strengthen the care of delivery and treatment of high-risk pregnancy,actively prevent related risk factors,and then reduce the incidence rate and mortality rate of HMD in newborn children.
出处
《中国全科医学》
CAS
北大核心
2017年第A01期161-163,共3页
Chinese General Practice
关键词
肺透明膜病
新生儿
危险因素
Hyaline membrane disease
Newborn
Risk factors