摘要
基质辅助激光解析电离飞行时间质谱（MALDI-TOF MS）作为一种快速、准确、高通量的细菌鉴定技术,已经开始逐步应用于临床微生物实验室.然而,MALDI-TOF MS的应用远不止细菌鉴定,其在细菌分型方面同样具有广阔的前景.基于MALDI-TOF MS的分型方法具有简单、快速、成本低廉、高通量等特点,可以在医院感染控制和暴发流行时发挥快速筛选的作用.
As a rapid, accurate and high throughput bacterial identification technique, matrix-assisted laser desorption ionization time of flight mass spectrometry（MALDI-TOF MS）has been gradually applied to clinical microbiological laboratories.However, the application of MALDI-TOF MS is far beyond the identification of bacteria.It also has broad application prospect in bacterial typing.The MALDI-TOF MS based typing method is simple, rapid, low-cost and high throughput, which can play an important role in nosocomial infections surveillance.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2017年第11期890-893,共4页
Chinese Journal of Laboratory Medicine
关键词
细菌分型技术
光谱法
质量
基质辅助激光解吸电离
Bacterial typing techniques
Spectrometry,mass,matrix-assisted laser desorption-ionization
