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糖尿病肾病患者心血管疾病患病率及其危险因素分析 被引量:22

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摘要 糖尿病患者的数量正在以惊人的速度在全球范围内迅速增加([1])。据2013年研究报道,我国糖尿病患病率达11.6%,患病人数居全球首位([2])。糖尿病肾病(diabetic nephropathy,DN)是糖尿病患者最常见的微血管并发症,严重影响糖尿病患者的预后,在欧美发达国家已成为慢性肾脏病(chronic kidney disease,CKD)的首要病因([3-5])。越来越多的证据表明.
作者 常沁涛
出处 《中国药物与临床》 CAS 2017年第11期1606-1608,共3页 Chinese Remedies & Clinics
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  • 1毛玉山,周丽诺,李福军,叶红英,杜娟,施淑钧,陈长喜,申定国,黄童,洪中立.中老年高尿酸血症对血管内皮功能的影响[J].中华风湿病学杂志,2006,10(3):169-171. 被引量:23
  • 2Hayden MR, Tyagi SC. Uric acid: a new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes meUitus : the urate redox shuttle. Nutr Metab ( Lond ), 2004,1:10.
  • 3Short RA. Johnson RJ, Turtle KR. Uric acid, microalbuminuria and cardiovascular events in hlgh-risk patients. Am J Nephrol, 2005,25:36-44.
  • 4Niskanen LK, Laaksonen DE, Nyyssonen K, et al. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middleaged men: a prospective cohort study. Arch Intern Med,2004, 164 : 1546-1551.
  • 5Bagnati M, Perugini C, Cau C, et al. When and why a watersoluble anfioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid. Biachem J, 1999,340 : 143-152.
  • 6Annuk M, Zilmer M, Lind L, et al. Oxidative stress and endothelial function in chronic renal failure. J Am Soc Ncphrol, 2001,12 : 2747 -2752.
  • 7Petrovi D, Stojimirovi B. Secondary hyperparathyroidism-risk factor for development of cardiovascular complications in patients on hemodialysis [J]. Med Pregl, 2010,63 (9-10) :674-680.
  • 8Chart, Jeong H J, Jang S P, et al. Parathyroid hormone accelerates decompensation following left ventricular hypertrophy [J]. Exp Mol Med, 2010, 42(1) :61-68.
  • 9Custodio M R, Koike M K, Neves K R, et al. Parathyroid hormone and phosphorus overload in uremia:impact on cardiovascular system [J]. Nephrol Dial Transplant, 2011,8. [Epub ahead of print].
  • 10Bonet J, Bayes B, Fernandez-Crespo P,et al. Cinacalcet may reduce arterial stiffness in patients with chronic renal disease and secondary hyperparathyroidism -results of a small- scale, prospective, observational study [J]. Clin Nephrol, March, 2011,75 (3) : 181-187.

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