摘要
目的观察邢台地区2013—2015年间育龄期妇女孕前甲状腺功能减退的情况,为育龄期妇女的孕前检查、优生优育提供科学依据。方法连续收集邢台市第三医院门诊2013—2015年间的育龄期妇女1058例,采用电化学发光法(试剂由Roche公司提供),在Roche全自动发光仪MYEGOI上进行游离甲状腺素(FT4)、促甲状腺激素(TSH)、甲状腺过氧化物酶抗体(TPO-Ab)的检测。选取TSH>4.2 m IU/L,FT4<12 pmol/L(或)FT4正常的甲减或亚临床甲减的妇女作为观察组,分析不同组间甲状腺功能减退的发生率。结果甲状腺功能异常的发生率随年龄增长而升高,其差异有统计学意义(P<0.05)。结论邢台地区育龄期妇女甲状腺功能异常的发生率随年龄增长而升高,是孕前化验的必要项目。
Objective To observe hypothyroidism of women at reproductive age in Xingtai Area from 2013 to 2015 to provide a scientific basis for eugenics and for the prepregnancy check of the women at reproductive age.Methods 1058 women at reproductive age enrolled were continuously collected.The markers of thyroid function,such as free thyroxine（FT4）,thyroid stimulating hormone（TSH） and thyroid peroxidase antibody（TPO-Ab）,were determined with the electrochemiluminescence immunoassay（Roche MYEGOI）.Hypothyroidism or subclinical hypothyroidism women were regarded as the observation group,and the incidence of thyroid disfunction in different groups was analyzed.Results The incidence of hypothyroidism increased with age.The difference was statistically significant（P〈0.05）.Conclusion The incidence of hypothyroidism of women at reproductive age in Xingtai is increasing with age.It is necessary to test the project before pregnancy.
出处
《黑龙江医学》
2017年第11期1130-1131,共2页
Heilongjiang Medical Journal
关键词
邢台地区
育龄期
甲状腺功能减退
Xingtai Area
Women of reproductive age
Hypothyroidism
