摘要
目的通过对艾滋病病毒(HIV)感染产妇分娩的新生儿的出生体格情况及其相关影响因素进行分析,为HIV感染产妇孕期保健服务提供指导。方法回顾性分析2005年3月至2016年6月11年期间HIV感染产妇分娩的新生儿出生体格的发育情况,与同期普通产妇分娩的新生儿进行比较。结果共调查11 129名新生儿,HIV感染产妇的新生儿310人,普通产妇的新生儿10 819人。HIV感染产妇平均分娩孕周[(38.6±1.4)周]低于普通产妇[(39.2±1.3)周],差异有统计学意义(P<0.05)。普通产妇所生新生儿体格发育情况优于HIV感染产妇所生新生儿(P<0.05),HIV感染产妇所生新生儿体重(2 988.9±275.5)g,头围(29.3±2.7)cm,胸围(28.5±2.3)cm,身长(49±1.9)cm;普通产妇所生新生儿体重(3 250.5±424.8)g,头围(32.3±1.9)cm,胸围(31.6±1.9)cm,身长(50.1±1.7)cm。HIV感染产妇在妊娠并发症发生率,以及妊娠并发肝炎、胎膜早破、妊娠并发性传播疾病、胎儿宫内窘迫、早产、妊娠并发贫血、妊娠并发甲状腺疾病、妊娠并发肝脏疾病和胎儿生长受限等情况均高于普通产妇,差异有统计学意义(P<0.05)。胎膜早破羊水细菌培养感染率HIV感染产妇高于普通产妇,差异有统计学意义(P=0.042)。结论 HIV感染会对孕产妇的孕周及新生儿出生体重产生影响,对于HIV感染孕产妇应加强孕期保健服务,规范抗病毒治疗、预防药物不良反应,安全助产,指导新生儿科学喂养,提高HIV产妇和婴儿的生存质量。
Objective To know the physique and related factors of neonates born to pregnant women with HIV infection, to improve health care during pregnancy of HIV infected women. Methods Comparison was made between the neonates borne to HIV infected mothers and normal mothers, from Mar. 2005 to Jun. 2016. Results The average gestational age was 38.6±1.4 weeks of HIV infected mothers, and 39.2±1.3 weeks of normal expectant mothers（P〈0. 05）. The neonates born to HIV infected women had average weight of 2988.9±275.5 g, head circumference of 29.3±2.7 cm, chest circumference of 28.5±2.3 cm, and length of 49±1.9 cm. And those born to non-infected mothers had better data of the same indicators such as 3250.5±424.8 g, 32.3±1.9 cm, 31.6±1.9 cm, 50.1±1.7 cm respectively（P〈0. 05）. The incidence of pregnancy complication or pregnancy coexisted diseases was higher in HIV infected women than non-infected women with the difference significant（P〈0. 05）, such as hepatitis, premature rupture of membrane, sexual diseases, fetal distress, premature delivery, fetal growth restriction, anemia, thyroid disorder, and hepatic disease, including amniotic fluid germiculture results（P=0.042）. Conclusion HIV infection has an effect on gestational weeks of pregnant women and birth weight of their neonates. These measures, such as improved pregnancy care services, regular antiviral therapy, prevention of adverse drug reactions, safe midwifery and instruction for neonatal feeding, should be taken to improve life quality of HIV infected women and their babies.
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2017年第11期1033-1035,共3页
Chinese Journal of Aids & STD
基金
促进农村孕产妇艾滋病
梅毒和乙肝母婴传播早期检测及阻断研究(2014NS369)~~
