摘要
目的了解钦州地区痛风和高尿酸血症的患病率及相关影响因素。方法采用问卷调查、体格检查及实验室检查等方式对钦州地区常住人口进行调查,统计痛风和高尿酸血症患病率,根据血尿酸水平分为高尿酸血症组和正常血尿酸组,比较两组生活习惯、合并疾病情况,分析不同年龄段不同性别高尿酸血症患病情况,采用多因素Logistic回归模型分析高尿酸血症的危险因素。结果 3 783例被调查者中痛风患病率1.67%(63/3 783),其中男性患病率2.81%(51/1 818),高于女性的0.61%(12/1 965),差异有统计学意义(P<0.05);男性血尿酸水平(377.49±72.52)μmol/L高于女性[(291.38±39.14)μmol/L],差异有统计学意义(P<0.05);高尿酸血症患病率21.04%(796/3 783),其中男性患病率26.90%(489/1 818)高于女性[15.62%(307/1 965)],差异有统计学意义(P<0.05);高尿酸血症组吸烟、饮酒、超重或肥胖、糖尿病、高血压、高胆固醇血症、高三酰甘油血症发生率依次为31.03%、41.96%、58.92%、11.18%、24.87%、10.93%、40.95%,与血尿酸正常组的17.01%、23.97%、37.93%、8.37%、12.76%、5.42%、15.97%比较,差异有统计学意义(P<0.05);男性、年龄≥50岁、超重或肥胖、饮酒、高胆固醇血症、高三酰甘油血症是高尿酸血症的危险因素(P<0.05)。结论钦州地区居民高尿酸血症及痛风患病率较高,应针对其危险因素采取早期预防措施,患者应积极治疗。
Objective To investigate prevalence and related factors of gout and high uric acid hematic disease in Qinzhou district.Methods The questionnaire,physical examination and laboratory examination methods were adopted to investigate the disease prevalence of gout and high uric acid hematic.According to the blood uric acid levels,subjects were divided into high blood uric acid group and normal blood uric acid group,living habits and the merger disease situation were compared between the two groups,high uric acid hematic disease prevalence in different ages between different genders were also analyzed.At the same time,using multivariable Logistic regression model,the dangerous factors of high uric acid hematic disease were analyzed.Results The gout prevalence in 3 783 cases was 1.67%（63/3 783）,which of the male and female were 2.81%（51/1 818）and 0.61%（12/1 965）,the difference was statistically significant（P〈0.05）.Blood uric acid level of male was（377.49±72.52）μmol/L,which was higher than that of female[（291.38±39.14）μmol/L],the difference was statistically significant（P〈0.05）.Prevalence rate of high uric acid hematic was 21.04%（796/3783）,which of the male and female were 26.90%（489/1 818）and 15.62%（307/1 965）,the difference was statistically significant（P〈0.05）.Rates of smoking,drinking,overweight or obesity,diabetes,high blood pressure,high cholesterol,high three acyl glycerin hematic disease in high uric acid hematic disease group were 31.03%,41.96%,58.92%,11.18%,24.87%,24.87%,10.93% and 40.95%,respectively,which of the normal group were 17.01%,23.97%,37.93%,8.37%,12.76%,5.42%and 15.97%,the difference was statistically significant（P〈0.05）.Male,age higher than 50 years,overweight or obesity,drinking,hypercholesterolemia,three acyl glycerin hematic disease were risk factors for high blood uric acid（P〈0.05）.Conclusion High blood uric acid and gout prevalence rate in Qinzhou district residents are higher,early prevention measures should be taken on the risk factors,patients should take active treatment.
出处
《检验医学与临床》
CAS
2017年第23期3470-3472,共3页
Laboratory Medicine and Clinic
基金
广西壮族自治区钦州市科学研究与技术开发计划项目(201514921)
关键词
痛风
高尿酸血症
流行病学
gout
high uric acid hematic disease
epidemiology
