摘要
目的分析医院感染患者中革兰阴性杆菌分布及其耐药情况,为指导临床合理用药提供依据。方法收集某综合医院2011-2016年医院感染患者送检病原学标本中分离的革兰阴性杆菌相关资料进行分析。结果调查期间共检出革兰阴性杆菌658株,其中大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌和鲍曼不动杆菌分居前4位,共520株,占检出总数的79.03%。医院感染革兰阴性杆菌主要分离自痰标本。对4种主要菌株的药敏试验结果显示,临床分离的革兰阴性杆菌中多重耐药菌株占检出革兰阴性杆菌总数的50.19%。结论该医院患者感染革兰阴性杆菌主要分离自痰标本,呈现普遍耐药,多重耐药菌占50%,应注意科学合理使用抗菌药物和强化耐药菌监测。
Objective To investigate distribution and drug resistance status of Gram-negative bacteria in nosocomial infection of hospital,so as to guide the reasonable clinical medication. Methods The data of Gram-negative strains isolated in a comprehensive hospital from 2011 to 2016 were collected to analyze. Results 658 strains of Gram-negative bacilli were detected out during the investigation. The first four were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa and Acinetobacter baumannii. The total of them was 520,which accounted for 79. 03%. Mainly were come from sputum.The drug sensitivity tests showed 50. 19% of the Gram negative bacilli were multi-drug resistance. Conclusion Most of Gram-negative bacteria in nosocomial infection of hospital are come from sputum,with commonly drug resistance. 50% of them were multi-drug resistance. Drug resistance monitoring should be strengthened and we should pay more attention to rational usage of drug.
出处
《中国消毒学杂志》
北大核心
2017年第10期936-938,共3页
Chinese Journal of Disinfection
关键词
医院感染
革兰阴性杆菌
耐药性
hospital infection
Gram - negative bacilli
drug resistance
