摘要
目的分析小儿病毒性哮喘的临床特点，探讨孟鲁斯特在小儿哮喘中的治疗效果。方法以本院92例小儿哮喘为观察对象，均确诊为呼吸道病毒感染，随机将其分成两组，每组46例，对照组在常规治疗基础上使用糖皮质激素，观察组在常规治疗基础上适量孟鲁司特联合糖皮质激素，比较两组的治疗效果。结果观察组治疗后症状评分和症状消失时间均明显好于对照组，观察组治疗总有效率为95．7％，对照组治疗总有效率为78．3％，组间总有效率比较差异有统计学意义；两组治疗后的FVC、FEV．和PEF肺功能指标均明显改善，观察组的改善效果更佳。两组治疗过程中未见明显副反应。结论小儿病毒性哮喘迁延难愈，孟鲁司特能提高小儿哮喘的疗效，有助于肺部功能的改善。
Objective To analyze the clinical features of children with viral asthma and explore the therapeutic effect of montelukast on children with asthma. Methods 92 children with asthma treated at our hospital were selected as observation objects and all were diagnosed respiratory tract infection. They wererandomly divided into a control group and an observation group, 46 cases for each group. Both groups were routinely treated; in addition, the control group were treated with glucocorticoid and the observation group with montelukast and glucocorticoid. The treatment effects were compared between these two groups. Results After the treatment, the symptom scores and symptom-disappeared time were significantly better in the observation group than in the control group. The total efficacy was 95.7% in the observation group and was 78.3% in the control group, with a statistical difference. After the treatment, the FVC, FEV~, and PEF were improve in both groups and were better in the observation group than in the control group. During the treatment, no obvious adverse reactions were found in both groups. Conclusions Children with asthma are protracted. Montelukast can improve the curative effect of children with asthma and helps to improve lung function.
出处
《国际医药卫生导报》
2017年第23期3704-3707,共4页
International Medicine and Health Guidance News
关键词
小儿病毒性哮喘
孟鲁司特
临床特点
疗效
Children with asthma
Montelukast
Clinical features
Curative effect
