摘要
复发性流产属于临床上难治疾病之一,严重影响女性的身心健康和家庭社会的稳定。其病因多与免疫因素、血栓前状态、感染、细胞凋亡、原癌基因及侵袭力等方面有关。随着研究深入,母胎界面血管生成障碍受到越来越多重视。从血管生成调控方面,介绍血管生成的促进因子及相关调控因子与复发性流产的关系,为中药干预复发性流产母胎界面血管生成障碍提供理论基础及依据。
Recurrent abortion belongs to one of refractory diseases, which seriously affects women＇ s physical and mental health and family social stability. Its etiology is connected with immune factors, former state thrombi,infection,apoptosis, proto-oncogene and aggressivity, etc. With the in-depth research, angiogenesis obstacle of maternal-fetal interface is taken more seriously. From the aspects of angiogenesis regulation, this paper introduced angiogenesisfactors and related regulatory factors in promoting relations with recurrent abortion, recurrent abortion of maternalfetal interface for traditional Chinese medicine intervention angiogenesis obstacles to provide theoretical foundation and basis.
作者
王媛中
李元琪
李伟莉
WANG Yuanzhong;LI Yuanqi;LI Weili(Anhui University of Chinese Medicine, Hefei 230038, China;Guangzhou University of Chinese Medicine, Guangzhou 510000, China;The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China)
出处
《长春中医药大学学报》
2017年第6期979-983,共5页
Journal of Changchun University of Chinese Medicine
基金
国家自然科学基金资助项目"补肾安胎冲剂改善RSA小鼠母胎界面血管生成障碍的机制研究"(81574017)
关键词
复发性流产
母胎界面
VEGF
HIF
调控因子
recurrent abortion
maternal-fetal interface
VEGF
HIF
regulatory factors
