摘要
目的:研究乙酰半胱氨酸泡腾片联合噻托溴铵粉吸入剂治疗慢性阻塞性肺疾病(COPD)的临床疗效。方法:选取2014年2月-2016年4月医院收治的慢性阻塞性肺疾病(COPD)患者124例,随机分为观察组和对照组,每组患者62例。在常规治疗基础上,对照组患者单独使用噻托溴铵粉吸入剂进行治疗,观察组患者采用乙酰半胱氨酸泡腾片联合噻托溴铵粉吸入剂进行治疗,比较两组患者治疗前后的FVC、FEV_1、FEV_1/FVC等指标,同时比较两组患者的总体治疗效果。结果:治疗前,两组患者FVC、FEV_1、FEV_1/FVC等指标比较差异均无统计学意义(P>0.05);治疗后,观察组患者FVC、FEV_1、FEV_1/FVC等指标均显著优于对照组患者,差异有统计学意义(P<0.05);治疗后,观察组患者治疗总有效率为90.32%,显著高于对照组患者的70.97%,比较差异有统计学意义(P<0.05)。结论:采用乙酰半胱氨酸泡腾片联合噻托溴铵粉吸入剂治疗COPD,能够取得更为理想的临床疗效。
Objective To study the clinical efficacy of Acetylcysteine Effervescent Tablet in combination with Tiotropium Bromide Powder for Inhalation for COPD patients.Method：From February 2014 to April 2016,124 patients with chronic obstructive pulmonary disease（COPD） admitted to hospital were randomly divided into the observation group and the control group,62 cases in each group.On the basis of conventional treatment,patients in the control group were treated with Tiotropium Bromide Powder for Inhalation alone,patients in the observation group were treated with Acetylcysteine Effervescent Tablets combined with Tiotropium Bromide Powder for Inhalation.The indexes of FVC,FEV1,FEV1/FVC before and after treatment in two groups were compared,and the overall effect of treatment were compared between two groups.Result：Before treatment,there were significant differences in the FVC,FEV1,FEV1/FVC and other indicators between the two groups（P〉0.05）.After treatment,the indexes of FVC,FEV1,FEV1/FVC in the observation group were significantly better than those in the control group（P〈0.05）.After treatment,the total effective rate of the observation group was 90.32%,which was significantly higher than that of control group 70.97%（P〈0.05）.Conclusion： The use of Acetylcysteine Effervescent Tablets combined with Tiotropium Bromide Powder for Inhalation for the treatment of COPD,can achieve more desirable clinical efficacy.
出处
《中外医学研究》
2017年第36期5-7,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
乙酰半胱氨酸泡腾片
噻托溴铵粉吸入剂
COPD
临床疗效
Acetylcysteine Effervescent Tablets
Tiotropium Bromide Powder for Inhalation
COPD
Clinical efficacy
