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他汀类药物治疗慢性心力衰竭的应用研究 被引量:3

Clinical effect and value of statins in treatment of chronic heart failure
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摘要 目的研究在治疗慢性心力衰竭中应用他汀类药物的临床效果与价值。方法本次我院研究样本为2015年12月至2016年12月期间收治的50例慢性心力衰竭患者,将随机数字表法作为分组形式,分成参照组(25例)与实验组(25例),将采取利尿剂、β受体阻滞剂、血管紧张素转换酶抑剂、醛固酮受体拮抗剂、血管扩张剂等患者作为参照组,将在常规治疗基础上增加他汀类药物患者作为实验组,分析对比两组慢性心力衰竭患者组间差异情况。结果实验组慢性心力衰竭患者治疗总有效率、心功能分级、心室射血分数、6min步行距离等与参照组各项数据进行对比存在显著差异且P<0.05,故存在统计学意义。结论将他汀类药物应用在慢性心力衰竭临床治疗中效果显著,可减少复发率,促进患者尽早恢复健康。 Objective To investigate the clinical effect and value of statins in the treatment of chronic heart failure. Methods A total of 50 patients with chronic heart failure who were admitted to our hospital from December 2015 to December 2016 were enrolled and divided into control group and experimental group using a random number table, with 25 patients in each group. The patients in the control group were given diuretic, β-receptor blocker, angiotensin-converting enzyme inhibitor, aldosterone receptor antagonist, or vasodilator, and those in the experimental group were given statins in addition to the conventional treatment. Related data were compared between the two groups. Results There were significant differences between the two groups in overall response rate, cardiac functional grading, ejection fraction, and distance in six-minute walk test (P〈0.05). Conclusion Statins have a marked clinical effect in the clinical treatment of chronic heart failure and can reduce recurrence and promote patients' recovery.
作者 李松华
机构地区 启东市人民医院
出处 《心血管病防治知识(学术版)》 2017年第11期53-55,共3页 Prevention and Treatment of Cardiovascular Disease
关键词 他汀类药物 慢性心力衰竭 应用 Statins Chronic heart failure Application
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