摘要
目的 分析玻璃体切除术后单疱病毒性角膜炎（HSK）复发的相关因素.方法 回顾性分析2010年3月至2016年7月曾患HSK者行玻璃体切除手术108例（108眼）的临床资料.其中部分患者术后单疱病毒性角膜炎复发.分别对复发者和未复发者术前、术中及术后的相关因素进行统计分析.结果 36眼在玻璃体切除术后HSK复发,发生率为33.33%.术中所用玻切头的大小、观察系统、眼内填充物、术后晶体囊是否完整与术后HSK复发无相关性;而年龄大小、有无糖尿病、术前单疱病毒性角膜炎发作次数、手术时间长短、手术方式、术中是否刮除角膜上皮、术后有无高眼压、有无角膜病变及有无感冒与术后HSK复发有相关性.结论 术后HSK的复发与影响角膜上皮细胞的功能及局部或全身免疫功能的因素有关.
Objective To analyze the related factors about the recurrence of herpes simplex keratitis （HSK） after vitrectomy.Methods The data of 108 eyes of 108 patients with HSK from Mar.2013 to Jul.2016 were collected and analyzed retrospectively .Herpes simplex keratitis was recurred in some patients after operation .The preoperative , intraoperative and postoperative factors related with recurrence of HSK were compared and analyed between the recurrent cases and no recurrent cases .Results In 108 eyes, 36 （33.3%） eyes were found recurrent HSK after vitrectomy.The size of vitrectomy cutter head, intraoperative observation system , intraocular tamponade , postoperative capsular membrane integrity were not relative with recurrence of HSK.And the age, diabetes, preoperative HSK recurrence times , operative time, surgical methods, corneal epithelial curettage , postoperative high intraocular pressure , corneal lesions and influenza were relative with recurrence of HSK .Conclusion The factors affected the function of corneal epithelial cells and the local or systemic immune are related with the postoperative recurrence of HSK .
作者
刘琳
张波
杨晔
郭宇燕
叶素娜
程浩
Liu L;Yang Y;Guo YY;Ye SN;Cheng H;Zhang B(Department of Ophthalmology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China;Zhongshan Ophthalmic Center, Sun Yasen University, Guangzhou 510060, China)
出处
《中华眼外伤职业眼病杂志》
2017年第12期936-939,共4页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
基金
广东省科技计划项目（20138022000086）
广东省公益研究与能力建设专项资金（2014A020212365）
广东省科技计划项目（20118031800112）
